Mouse NUP160 (Nucleoporin 160kDa) CLIA Kit | NUP160 clia kit

Mouse NUP160 (Nucleoporin 160kDa) CLIA Kit

Cat. Num. AAA2532105

• Reactivity: Mouse
• Synonyms: NUP160 (Nucleoporin 160kDa); Mouse NUP160 (Nucleoporin 160kDa) CLIA Kit; NUP160 clia kit

• Reactivity: Mouse
• Specificity: This kit recognizes natural and recombinant NUP160. No significant cross-reactivity or interference between NUP160 and analogues was observed.
• Sequence Length: 1436

• Assay Type: Sandwich
• Detection Range: 31.25-2000pg/mL
• Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for NUP160 clia kit

Intended Uses: This CLIA kit applies to the in vitro quantitative determination of NUP160 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to NUP160. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for NUP160 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain NUP160, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of NUP160. You can calculate the concentration of NUP160 in the samples by comparing the RLU value of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 115528953
• NCBI GeneID: 23279
• Molecular Weight: 55,554 Da
• NCBI Official Full Name: Nucleoporin 160kDa
• NCBI Official Synonym Full Names: nucleoporin 160kDa
• NCBI Official Symbol: NUP160
• NCBI Protein Information: nuclear pore complex protein Nup160
• UniProt Protein Name: Nuclear pore complex protein Nup160
• Protein Family: Nuclear pore complex protein
• UniProt Gene Name: NUP160
• UniProt Synonym Gene Names: KIAA0197; NUP120
• UniProt Entry Name: NU160_HUMAN

NCBI Description

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]

Uniprot Description

NUP160: Involved in poly(A)+ RNA transport. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: kinetochore; nuclear envelope; nuclear pore; cytosol

Molecular Function: protein binding; nucleocytoplasmic transporter activity

Biological Process: viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; viral infectious cycle; glucose transport; post-translational protein modification; protein transport; mRNA export from nucleus; protein sumoylation; cellular protein metabolic process; small GTPase mediated signal transduction; hexose transport; carbohydrate metabolic process; viral transcription; gene expression; mitotic cell cycle; transmembrane transport