Testing Data
anti-Mouse Kinase D-interacting substrate 220 Antibody | anti-Wdr18 antibody
Kinase D-interacting substrate 220 Antibody
Gene Names
Wdr18; AU044733; AW122032; 2310012I10Rik
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry
Synonyms
Kinase D-interacting substrate 220; Kinase D-interacting substrate 220 Antibody; anti-Wdr18 antibody
Reactivity
Mouse
Clone Number
3-B6
Specificity
This antibody is produced by immunizing mouse with recombinant protein Kidins220.
Form/Format
In 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Sequence Length
431
Applicable Applications for anti-Wdr18 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
WB: 1:500~1:1,000
ICC 1:100~1:500
ICC 1:100~1:500
Preservative
0.05% Sodium Azide.
Cellular Localization
Cell Membrane
Positive Control
Recombinat protein
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-Wdr18 antibody
Kinase D-interacting substrate 220 (Kidins220), also known as ARMS (ankyrin-rich membrane spanning) is an integral plasma membrane protein predominantly expressed in brain and neurons that presents a polarized location in neural cells, concentrating at the tip of extending neurites and in plasma membrane micro-domains corresponding to lipid rafts. The primary amino acid sequence of Kidins220 reveals 11 ankyrin repeats, 4 trans-membrane domains, a proline-rich region, a sterile-alpha motif (or SAM) domain, and a type I postsynaptic density-95/discs large/zonula occludens-1 (PDZ)-binding motif at the very C-terminus.
References
"Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D." Iglesias T, Cabrera-Poch N, Mitchell MP, Naven TJ, Rozengurt E, Schiavo G. J Biol Chem. 22; 275(51):40048-56(2000). "Large-scale phosphorylation analysis of mouse liver."Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48kDa
NCBI Official Full Name
WD repeat-containing protein 18
NCBI Official Synonym Full Names
WD repeat domain 18
NCBI Official Symbol
Wdr18
NCBI Official Synonym Symbols
AU044733; AW122032; 2310012I10Rik
NCBI Protein Information
WD repeat-containing protein 18
UniProt Protein Name
WD repeat-containing protein 18
Protein Family
UniProt Gene Name
Wdr18
Uniprot Description
May play a role during development (). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
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Product Notes
The Wdr18 wdr18 (Catalog #AAA850625) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Kinase D-interacting substrate 220 Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Kinase D-interacting substrate 220 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). WB: 1:500~1:1,000 ICC 1:100~1:500. Researchers should empirically determine the suitability of the Wdr18 wdr18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kinase D-interacting substrate 220, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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