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MCP5 active protein

MCP5 protein (Mouse)

Gene Names
mcp5; mug21; num1
Applications
User optimized
Purity
> 98% pure
Synonyms
MCP5; MCP5 protein (Mouse); MCP-5; CCL12 protein; MCP-5 protein; MCP 5; Monocyte Chemotactic Protein-5 protein; MCP 5 protein; MCP5 active protein
Ordering
For Research Use Only!
Host
Mouse
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Sequence
Region of MCP5 protein corresponding to amino acids GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG.
Sequence Length
968
Applicable Applications for MCP5 active protein
User optimized
Protein Type
Recombinant
Biological Significance
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species.
Bioactivity
Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-50.0 ng/ml.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for MCP5 active protein
Purified recombinant Mouse MCP5 protein
Product Categories/Family for MCP5 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
9.3 kDa
NCBI Official Full Name
Meiotic coiled-coil protein 5
NCBI Official Symbol
mcp5
NCBI Official Synonym Symbols
mug21; num1
NCBI Protein Information
cortical anchoring factor for dynein Mcp5/Num1
UniProt Protein Name
Meiotic coiled-coil protein 5
UniProt Gene Name
mcp5
UniProt Synonym Gene Names
mug21; num1
UniProt Entry Name
MCP5_SCHPO

Uniprot Description

Involved in chromosome segregation. Facilitates nuclear oscillation during meiotic prophase I, the 'horsetail' phase, by acting as a dynein anchor. Essential for anchoring dhc1 to the cortex. Required for proper sliding of the microtubules along the cell cortex, which leads to the proper U-turn movement of the nucleus.

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Product Notes

The MCP5 mcp5 (Catalog #AAA539559) is an Active Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MCP5 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the MCP5 mcp5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of MCP5 protein correspond ing to amino acids GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG. It is sometimes possible for the material contained within the vial of "MCP5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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