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Mouse anti-Human ZW10 Monoclonal Antibody | anti-ZW10 antibody

ZW10 (Centromere/kinetochore Protein zw10 Homolog, zw10 Kinetochore Protein, HZW10, KNTC1AP) (MaxLight 750)

Gene Names
ZW10; HZW10; KNTC1AP
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ZW10; Monoclonal Antibody; ZW10 (Centromere/kinetochore Protein zw10 Homolog; zw10 Kinetochore Protein; HZW10; KNTC1AP) (MaxLight 750); anti-ZW10 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2E5
Specificity
Recognizes human ZW10.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Sequence Length
2873
Applicable Applications for anti-ZW10 antibody
FLISA, Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Partial recombinant corresponding to aa1-100 from ZW10 (NP_004715) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
masfvtevla hsgrlekedl gtrisrltrr veeikgevcn miskkysefl psmqsaqgli tqvdklsedi dllksriese vrrdlhvstg eftdlkqqle
Conjugate
MaxLight750
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for anti-ZW10 antibody
MaxLight750 is a new Near IR stable dye conjugate comparable to DyLight750, Alexa Fluor700 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (759nm); Emission (780nm); Extinction Coefficient 240,000.
Product Categories/Family for anti-ZW10 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
Homo sapiens zw10 kinetochore protein (ZW10), mRNA
NCBI Official Synonym Full Names
zw10 kinetochore protein
NCBI Official Symbol
ZW10
NCBI Official Synonym Symbols
HZW10; KNTC1AP
NCBI Protein Information
centromere/kinetochore protein zw10 homolog
UniProt Protein Name
Centromere/kinetochore protein zw10 homolog
Protein Family
UniProt Gene Name
ZW10
UniProt Entry Name
ZW10_HUMAN

NCBI Description

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011]

Uniprot Description

ZW10: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. Belongs to the ZW10 family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: kinetochore microtubule; kinetochore; spindle pole; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytoplasm; cytosol; nucleus

Molecular Function: centromeric DNA binding; protein binding

Biological Process: meiosis; ER to Golgi vesicle-mediated transport; protein transport; mitotic sister chromatid segregation; establishment of mitotic spindle orientation; cell division; mitotic cell cycle checkpoint; regulation of exit from mitosis; protein complex assembly; mitotic cell cycle; mitotic metaphase plate congression; Golgi organization and biogenesis

Research Articles on ZW10

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Product Notes

The ZW10 zw10 (Catalog #AAA6236279) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ZW10 (Centromere/kinetochore Protein zw10 Homolog, zw10 Kinetochore Protein, HZW10, KNTC1AP) (MaxLight 750) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZW10 can be used in a range of immunoassay formats including, but not limited to, FLISA, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ZW10 zw10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZW10, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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