Mouse anti-Human VWA1 Monoclonal Antibody | anti-VWA1 antibody
VWA1 (von Willebrand Factor A Domain-containing Protein 1, WARP)
Gene Names
VWA1; WARP; FLJ22215; DKFZp761O051
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
VWA1; Monoclonal Antibody; VWA1 (von Willebrand Factor A Domain-containing Protein 1; WARP); Anti -VWA1 (von Willebrand Factor A Domain-containing Protein 1; anti-VWA1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10K63
Specificity
Recognizes human VWA1 (aa19-445). Species sequence homology: mouse, rat (72%).
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS.
Applicable Applications for anti-VWA1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA:2ug/ml
Western Blot: 0.5-1ug/ml
Dilution: ELISA:2ug/ml
Western Blot: 0.5-1ug/ml
Immunogen
Purified, NS0-derived, recombinant human WARP (aa19-445; Accession #Q6PCB0).
Hybridoma
Fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human WARP.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-VWA1 antibody
Von Willebrand factor A (vWFA) domain-related protein (WARP) is a 50kD glycoprotein member of the vWFA domain superfamily of extracellular matrix proteins. It is expressed in embryonic articular cartilage, skeletal muscle and basement membranes in the PNS. WARP forms disulfide-linked homodimers and multimers, and complexes with perlecan. Secreted human WARP contains a vWFA domain (aa34-213), two fibronectin type III domains (aa211-301 and 331-421) that likely bind to the GAG modification of perlecan, and one potential site for N-linked glycosylation. There is one alternate start site at Met213. Mature human WARP is 72% aa identical to mature mouse and rat WARP.
Product Categories/Family for anti-VWA1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,804 Da
NCBI Official Full Name
von Willebrand factor A domain-containing protein 1 isoform 2
NCBI Official Synonym Full Names
von Willebrand factor A domain containing 1
NCBI Official Symbol
VWA1
NCBI Official Synonym Symbols
WARP; FLJ22215; DKFZp761O051
NCBI Protein Information
von Willebrand factor A domain-containing protein 1; OTTHUMP00000003018; OTTHUMP00000220538; von Willebrand factor A domain-related protein
UniProt Protein Name
von Willebrand factor A domain-containing protein 1
Protein Family
UniProt Gene Name
VWA1
UniProt Entry Name
VWA1_HUMAN
NCBI Description
VWA1 belongs to the von Willebrand factor (VWF; MIM 613160) A (VWFA) domain superfamily of extracellular matrix proteins and appears to play a role in cartilage structure and function (Fitzgerald et al., 2002 [PubMed 12062410]).[supplied by OMIM]
Uniprot Description
VWA1: Promotes matrix assembly. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: extracellular space; basement membrane
Molecular Function: identical protein binding
Biological Process: extracellular matrix organization and biogenesis; behavioral response to pain
Research Articles on VWA1
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Product Notes
The VWA1 vwa1 (Catalog #AAA631668) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The VWA1 (von Willebrand Factor A Domain-containing Protein 1, WARP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VWA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA:2ug/ml Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the VWA1 vwa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VWA1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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