Immunohistochemistry (IHC)
(Immunochemical staining of human C10orf54 in human kidney with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.)
Mouse anti-Human VISTA Monoclonal Antibody | anti-Vsir antibody
Anti-VISTA Antibody, Mouse Monoclonal
Gene Names
VSIR; B7H5; GI24; B7-H5; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A
Synonyms
VISTA; Monoclonal Antibody; Anti-VISTA Antibody; Mouse Monoclonal; VISTA/GI24/B7-H5 Antibody; Mouse MAb; V-set immunoregulatory receptor; Anti-B7-H5 Antibody; Anti-B7H5 Antibody; Anti-C10orf54 Antibody; Anti-DD1alpha Antibody; Anti-GI24 Antibody; Anti-PD-1H Antibody; Anti-PP2135 Antibody; Anti-SISP1 Antibody; anti-Vsir antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
027
Specificity
Human VISTA/GI24/B7-H5
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-Vsir antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:30-1:100
Immunogen
Recombinant Human VISTA/GI24/B7-H5 Protein
Conjugation
Unconjugated
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VISTA/GI24/B7-H5 (rh VISTA/GI24/B7-H5). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human C10orf54 in human kidney with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human C10orf54 in human kidney with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-Vsir antibody
VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells. VSIR is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6, and Monckeberg Arteriosclerosis. An important paralog of this gene is VSIG8.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
33,908 Da
NCBI Official Full Name
Chromosome 10 open reading frame 54
NCBI Official Synonym Full Names
V-set immunoregulatory receptor
NCBI Official Symbol
VSIR
NCBI Official Synonym Symbols
B7H5; GI24; B7-H5; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha
NCBI Protein Information
V-type immunoglobulin domain-containing suppressor of T-cell activation
Research Articles on Vsir
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Product Notes
The Vsir (Catalog #AAA8106950) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-VISTA Antibody, Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VISTA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:30-1:100. Researchers should empirically determine the suitability of the Vsir for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VISTA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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