Testing Data
(Flow cytometric analysis of Human VCAM1 expression on HUT78 cells. Cells were stained with APC-conjugated anti-Human VCAM1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)
Rabbit anti-Human VCAM1 Monoclonal Antibody | anti-VCAM1 antibody
Recombinant Anti-VCAM1 Antibody (APC), Rabbit Monoclonal
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
VCAM1; Monoclonal Antibody; Recombinant Anti-VCAM1 Antibody (APC); Rabbit Monoclonal; VCAM-1/CD106 Antibody (APC); Rabbit MAb; Anti-CD106 Antibody; Anti-INCAM-100 Antibody; Anti-VCAM-1 Antibody; vascular cell adhesion molecule 1; anti-VCAM1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
601
Specificity
Human VCAM-1/CD106
Purity/Purification
Protein A
Form/Format
Liquid. Aqueous solution containing 0.5% BSA and 0.03% ProClin300
Concentration
5ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-VCAM1 antibody
Flow Cytometry (FC/FACS)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human VCAM-1/CD106 Protein
Conjugation
APC
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human VCAM-1/CD106 (rh VCAM-1/CD106; NP_001069.1; Met1-Pro697) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze!
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Testing Data
(Flow cytometric analysis of Human VCAM1 expression on HUT78 cells. Cells were stained with APC-conjugated anti-Human VCAM1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)
Testing Data
(Flow cytometric analysis of Human VCAM1 expression on HUT78 cells. Cells were stained with APC-conjugated anti-Human VCAM1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)
Related Product Information for anti-VCAM1 antibody
Background: Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains are generated by alternative splicing, with the longer form predominant. VCAM-1 is an endothelial ligand for very late antigen-4 (VLA-4) and alpha4beta7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. VCAM-1 has been identified as a potential anti-inflammatory therapeutic target, the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.
References
Cook-Mills JM. (2002) VCAM-1 signals during lymphocyte migration: role of reactive oxygen species. Mol Immunol. 39(9): 499-508.
Preiss DJ, et al. (2007) Vascular cell adhesion molecule-1: a viable therapeutic target for atherosclerosis Int J Clin Pract. 61(4): 697-701.
Preiss DJ, et al. (2007) Vascular cell adhesion molecule-1: a viable therapeutic target for atherosclerosis Int J Clin Pract. 61(4): 697-701.
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Product Notes
The VCAM1 (Catalog #AAA8118910) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-VCAM1 Antibody (APC), Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VCAM1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the VCAM1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VCAM1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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