Quality Control
(Left: Western blot analysis of immunized recombinant protein, using anti-VAX2 monoclonal antibody.)
Mouse anti-Human VAX2 Monoclonal Antibody | anti-VAX2 antibody
Mouse monoclonal antibody Anti-Human VAX2
Quality Control
(Left: Western blot analysis of immunized recombinant protein, using anti-VAX2 monoclonal antibody.)
Quality Control
(Left: Western blot analysis of immunized recombinant protein, using anti-VAX2 monoclonal antibody.)
Western Blot (WB)
(Detection of VAX2 by Western blot.Samples: Whole cell lysate from human A2058 (H, 50 ug) and mouse NIH3T3 (M, 50 ug) cells. [Lot No. VAX2A8F12-1]Predicted molecular weight: 30 kDa)
Western Blot (WB)
(Detection of VAX2 by Western blot.Samples: Whole cell lysate from human A2058 (H, 50 ug) and mouse NIH3T3 (M, 50 ug) cells. [Lot No. VAX2A8F12-1]Predicted molecular weight: 30 kDa)
Immunocytochemistry (ICC)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-VAX2 mAb. [Lot No. VAX2A8F12-1])
Immunocytochemistry (ICC)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-VAX2 mAb. [Lot No. VAX2A8F12-1])
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development. [provided by RefSeq, Sep 2008]
Uniprot Description
VAX2: Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle. May be a regulator of axial polarization in the retina. Belongs to the EMX homeobox family.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 2p13
Cellular Component: cytoplasm; nucleus
Molecular Function: chromatin DNA binding; sequence-specific DNA binding; transcription factor activity
Biological Process: Wnt receptor signaling pathway; axonogenesis; visual perception; transcription, DNA-dependent; retina development in camera-type eye; embryonic eye morphogenesis; forebrain development; ectoderm development; dorsal/ventral axis specification; negative regulation of transcription from RNA polymerase II promoter
Research Articles on VAX2
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Product Notes
The VAX2 vax2 (Catalog #AAA120094) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human VAX2 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VAX2 can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB). Researchers should empirically determine the suitability of the VAX2 vax2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VAX2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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