Mouse VAMP 1,2 Monoclonal Antibody | anti-VAMP1 antibody

VAMP 1,2 (Vesicle-Associated Membrane Protein, Synaptobrevin)

Cat. Num. AAA606860

• Gene Names: VAMP1; SYB1; VAMP-1; DKFZp686H12131
• Reactivity: Hamster, Human, Porcine, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Ascites; Ascites
• Synonyms: VAMP 1; 2; Monoclonal Antibody; 2 (Vesicle-Associated Membrane Protein; Synaptobrevin); Anti -VAMP 1; anti-VAMP1 antibody

• Host: Mouse
• Reactivity: Hamster, Human, Porcine, Rat
• Clonality: Monoclonal
• Isotype: IgM
• Clone Number: 2Q109
• Specificity: Recognizes Synaptobrevin (VAMP). Reacts with VAMP-1 and VAMP-2 fusion protein expressed in bacterial system. Species Crossreactivity: Human, porcine, hamster, rat and salamander.
• Purity/Purification: Ascites; Ascites
• Form/Format: Supplied as a liquid, 0.1% sodium azide.

• Applicable Applications for anti-VAMP1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: Western Blot: 1:100-1:1,000; Immunohistochemistry: > 1:25
• Immunogen: Crude synaptic immunoprecipitate (Human)
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for anti-VAMP1 antibody

Antibodies; Abs to Membrane Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 40549446
• NCBI GeneID: 6843
• NCBI Accession #: NP_954740.1
• NCBI GenBank Nucleotide #: NM_199245.1
• UniProt Accession #: P23763; O75468; Q15857; Q6FG94; Q8IVC9; A8MVP3; D3DUR3
• Molecular Weight: 12,902 Da
• NCBI Official Full Name: vesicle-associated membrane protein 1 isoform 2
• NCBI Official Synonym Full Names: vesicle-associated membrane protein 1 (synaptobrevin 1)
• NCBI Official Symbol: VAMP1
• NCBI Official Synonym Symbols: SYB1; VAMP-1; DKFZp686H12131
• NCBI Protein Information: vesicle-associated membrane protein 1; synaptobrevin 1; synaptobrevin-1; OTTHUMP00000238453; OTTHUMP00000238454; OTTHUMP00000238455; OTTHUMP00000238560; OTTHUMP00000238561
• UniProt Protein Name: Vesicle-associated membrane protein 1
• Protein Family: Vesicle-associated membrane protein
• UniProt Gene Name: VAMP1
• UniProt Synonym Gene Names: SYB1
• UniProt Entry Name: VAMP1_HUMAN

NCBI Description

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq]

Uniprot Description

VAMP1: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p

Cellular Component: SNARE complex; synaptic vesicle; mitochondrial outer membrane; neuron projection; cell surface; synaptic vesicle membrane; integral to plasma membrane; cytosol; cell junction

Molecular Function: SNAP receptor activity; SNARE binding; protein binding

Biological Process: vesicle fusion; exocytosis; pathogenesis

Disease: Spastic Ataxia 1, Autosomal Dominant