Rabbit USO1 Monoclonal Antibody | anti-USO1 antibody

USO1 Rabbit mAb

Cat. Num. AAA4753094

• Gene Names: USO1; TAP; VDP; P115
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunoprecipitation
• Purity: Affinity purified
• Synonyms: USO1; Monoclonal Antibody; USO1 Rabbit mAb; General vesicular transport factor p115; TAP; VDP; P115; anti-USO1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone Number: R07-4B8
• Purity/Purification: Affinity purified
• Form/Format: Supplied in 50nM Tris-Glycine (pH7.4), 0.15M Nacl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

• Applicable Applications for anti-USO1 antibody: Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: WB: 1:1000-1:2000; IP: 1:20
• Immunogen: A synthetic peptide of human Vesicle docking protein p115
• Conjugation: Unconjugated
• Modification: Unmodification
• Subcellular Location: Cytoplasm, Golgi apparatus, Membrane
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot detection of USO1 in 3T3 cell lysates using USO1 Rabbit mAb(1:1000 diluted). Predicted band size:108kDa. Observed band size:108kDa.)

Related Product Information for anti-USO1 antibody

The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.

NCBI and Uniprot Product Information

• NCBI GI #: 143743108
• NCBI GeneID: 8615
• UniProt Accession #: O60763; Q6PK63; Q86TB8; Q8N592; B2RAQ0
• Molecular Weight: 962
• NCBI Official Full Name: General vesicular transport factor p115
• NCBI Official Synonym Full Names: USO1 vesicle transport factor
• NCBI Official Symbol: USO1
• NCBI Official Synonym Symbols: TAP; VDP; P115
• NCBI Protein Information: general vesicular transport factor p115; vesicle docking protein p115; transcytosis associated protein; USO1 vesicle docking protein homolog
• UniProt Protein Name: General vesicular transport factor p115
• Protein Family: General vesicular transport factor
• UniProt Gene Name: USO1
• UniProt Synonym Gene Names: VDP; TAP
• UniProt Entry Name: USO1_HUMAN

NCBI Description

The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Uniprot Description

TAP: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. Belongs to the VDP/USO1/EDE1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Vesicle

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: Golgi membrane; Golgi apparatus; Golgi stack; membrane; endoplasmic reticulum; perinuclear region of cytoplasm; nucleolus; cytosol

Molecular Function: protein transporter activity

Biological Process: intracellular protein transport; ER to Golgi vesicle-mediated transport; Golgi vesicle docking; vesicle fusion with Golgi apparatus; transcytosis; mitotic cell cycle