Western Blot (WB)
(Western Blot detection against Immunogen (37.22kD).)
Mouse anti-Human UPF3A Monoclonal Antibody | anti-UPF3A antibody
UPF3A (Up-frameshift Suppressor 3 Homolog A, hUpf3, UPF3, Nonsense mRNA Reducing Factor 3A, Regulator of Nonsense Transcripts 3A, RENT3A) APC
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western Blot detection against Immunogen (37.22kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (37.22kD).)
Western Blot (WB)
(Western Blot analysis of UPF3A expression in transfected 293T cell line by UPF3A monoclonal antibody. Lane 1: UPF3A transfected lysate (51kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of UPF3A expression in transfected 293T cell line by UPF3A monoclonal antibody. Lane 1: UPF3A transfected lysate (51kD). Lane 2: Non-transfected lysate.)
Immunohistochemistry (IHC)
(Immunoperoxidase of monoclonal antibody to UPF3A on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3ug/ml].)
Immunohistochemistry (IHC)
(Immunoperoxidase of monoclonal antibody to UPF3A on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3ug/ml].)
Testing Data
(Detection limit for recombinant GST tagged UPF3A is 0.03ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged UPF3A is 0.03ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Research Articles on UPF3A
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Product Notes
The UPF3A (Catalog #AAA6139778) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The UPF3A (Up-frameshift Suppressor 3 Homolog A, hUpf3, UPF3, Nonsense mRNA Reducing Factor 3A, Regulator of Nonsense Transcripts 3A, RENT3A) APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UPF3A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 3ug/ml Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the UPF3A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UPF3A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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