Testing Data
Mouse Transglutaminase-3 Monoclonal Antibody | anti-TG3 antibody
Transglutaminase-3 (TG3) Monoclonal Antibody
Applications
Immunoblot, Western Blot, Immunocytochemistry
Synonyms
Transglutaminase-3; Monoclonal Antibody; Transglutaminase-3 (TG3) Monoclonal Antibody; Anti-Transglutaminase-3 (TG3); anti-TG3 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody recognizes full-length human TG3 (77kDa) and the proteolysed form of human TG3 (30-47kDa).
Form/Format
100ug, Protein A-purified, lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.
Sequence Length
2
Applicable Applications for anti-TG3 antibody
Immunoblot (IB), Immunocytochemistry (ICC)
Application Notes
Immunoblotting: Use at 1-5ug/ml. Bands of ~77kDa and ~30kDa are detected.
Immunocytochemistry: Use at 2-10ug/ml.
Immunocytochemistry: Use at 2-10ug/ml.
Antigen
Recombinant human TG3 (accession no. Q08188).
Preparation and Storage
This product is stable for at least one (1) year at -20 degree C to -70 degree C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-TG3 antibody
Transglutaminase-3 (TG3), an epidermal-type enzyme, is responsible for formation of the epidermis. During keratinocyte differentiation, TG1 and TG3 appear to act cooperatively in the cross-linking of proteins, including involucrin, loricrin and small proline-rich proteins (SPRs). These reactions result in formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Furthermore, TG3 in hair follicles is involved in cross-linking structural proteins such as trichohyalin and keratin intermediate to hardening the inner root sheath. During differentiation in these processes, a zymogen form of TG3 (77 kDa) is activated by limited proteolysis with cathepsins S and/or L.
Product Categories/Family for anti-TG3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
transglutaminase 3, partial
Similar Products
Product Notes
The TG3 (Catalog #AAA190959) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Transglutaminase-3 can be used in a range of immunoassay formats including, but not limited to, Immunoblot (IB), Immunocytochemistry (ICC). Immunoblotting: Use at 1-5ug/ml. Bands of ~77kDa and ~30kDa are detected. Immunocytochemistry: Use at 2-10ug/ml. Researchers should empirically determine the suitability of the TG3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transglutaminase-3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
