Transferrin Recombinant Antibody | TF recombinant antibody
Anti-Transferrin [TW4.20]
Gene Names
TF; TFQTL1; PRO1557; PRO2086; HEL-S-71p
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Protein A Affinity Purified
Synonyms
Transferrin; Monoclonal Recombinant Antibody; Anti-Transferrin [TW4.20]; Serotransferrin; TF recombinant antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1, Kappa
Clone Number
TW4.20
Specificity
Binds to the N-terminal domain of human transferrin.
Purity/Purification
Protein A Affinity Purified
Concentration
1 mg/ml (varies by lot)
Sequence Length
698
Applicable Applications for TF recombinant antibody
Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Block (BL)
Application Notes
This antibody recognises transferrin a protein which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. This antibody can displace transferrin from the transferrin receptor.
Immunogen
Iron-free purified human transferrin.
Buffer Composition
PBS only with 0.02% Proclin 300.
Labeled Substance
None
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for TF recombinant antibody
Recombinant monoclonal antibody to Transferrin. Manufactured using a proprietary Recombinant Platform with variable regions (i.e. specificity) from the hybridoma TW4.20.
Iron-free purified human transferrin.
Iron-free purified human transferrin.
Product Categories/Family for TF recombinant antibody
References
Orlandini et al. Cloning, characterization, and modeling of a monoclonal antihuman transferrin antibody that competes with the transferrin receptor Protein Sci. 3 (9), 1476-1484 (1994) PMID:7530542
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
76,960 Da
NCBI Official Full Name
serotransferrin isoform 1
NCBI Official Synonym Full Names
transferrin
NCBI Official Symbol
TF
NCBI Official Synonym Symbols
TFQTL1; PRO1557; PRO2086; HEL-S-71p
NCBI Protein Information
serotransferrin
UniProt Protein Name
Transferrin
Protein Family
UniProt Gene Name
TF
NCBI Description
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
Research Articles on TF
Similar Products
Product Notes
The TF tf (Catalog #AAA488339) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Transferrin [TW4.20] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transferrin can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Block (BL). This antibody recognises transferrin a protein which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. This antibody can displace transferrin from the transferrin receptor. Researchers should empirically determine the suitability of the TF tf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transferrin, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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