Mouse anti-Human TNFRSF1A Monoclonal Antibody | anti-TNFRSF1A antibody

Anti-TNFRSF1A Antibody, Mouse Monoclonal

Cat. Num. AAA8118977

• Reactivity: Human
• Applications: ELISA
• Purity: Protein A
• Synonyms: TNFRSF1A; Monoclonal Antibody; Anti-TNFRSF1A Antibody; Mouse Monoclonal; TNFRSF1A Antibody; Mouse MAb; Anti-CD120a Antibody; Anti-FPF Antibody; Anti-MS5 Antibody; Anti-p55 Antibody; Anti-p55-R Antibody; Anti-p60 Antibody; Anti-TBP1 Antibody; Anti-TNF-R Antibody; Anti-TNF-R-I Antibody; Anti-TNF-R55 Antibody; Anti-TNFAR Antibody; Anti-TNFR1 Antibody; Anti-TNFR1-d2 Antibody; Anti-TNFR55 Antibody; Anti-TNFR60 Antibody; tumor necrosis factor receptor superfamily member 1A; anti-TNFRSF1A antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Clone Number: 9
• Specificity: Human TNFRSF1A
• Purity/Purification: Protein A
• Form/Format: Liquid. 0.2um filtered solution in PBS

• Applicable Applications for anti-TNFRSF1A antibody: ELISA (EIA)(Det)
• Immunogen: Recombinant Human TNFRSF1A Protein
• Conjugation: Unconjugated
• Preparation: This product is a recombinant monoclonal antibody expressed from HEK293 cells.
• Notes: ELISA(Det): This antibody will detect Human TNFR1/TNFRSF1A/CD120a in ELISA pair set. In a sandwich ELISA, it can be used as detection antibody when paired with.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.; This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Related Product Information for anti-TNFRSF1A antibody

Background: The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1/TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-kappaB, mediate apoptosis, and regulate inflammation processes.

Product Categories/Family for anti-TNFRSF1A antibody

Neuroinflammation; Death Receptor Signaling

References

Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.