Immunoblot (IB)
(A 1:1000 dilution was sufficient for detection of TNFRSF18 in 10 ug of Mouse skeletal muscle by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.)
Mouse anti-Human, Mouse TNFRSF18 Monoclonal Antibody | anti-TNFRSF18 antibody
TNFRSF18 Antibody
Gene Names
TNFRSF18; AITR; GITR; CD357; GITR-D
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein G Purified
Synonyms
TNFRSF18; Monoclonal Antibody; TNFRSF18 Antibody; Mouse Anti-Human TNFRSF18 Monoclonal IgG2b; Clone T9P4G4-D7; Activation inducible TNFR family receptor antibody; AITR antibody; CD357 antibody; GITR antibody; GITRD antibody; Glucocorticoid induced TNFR related protein antibody; glucocorticoid-induced tnf receptor ligand antibody; Glucocorticoid-induced TNFR-related protein antibody; TNF receptor superfamily activation inducible protein antibody; TNFRSF 18 antibody; TNR18_HUMAN antibody; Tumor necrosis factor receptor superfamily member 18 antibody; Tumor necrosis factor receptor superfamily member 18 precursor antibody; anti-TNFRSF18 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
T9P4G4-D7
Specificity
Detects 25 kDa. Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Purity/Purification
Protein G Purified
Form/Format
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-TNFRSF18 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000
Immunogen
Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18
Immunogen Species
Human
Conjugate
Unconjugated
Cellular Localization
Secreted, Cell Membrane
Certificate of Analysis
A 1:1000 dilution was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 ug of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Preparation and Storage
Store at-20 degree C.
Immunoblot (IB)
(A 1:1000 dilution was sufficient for detection of TNFRSF18 in 10 ug of Mouse skeletal muscle by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.)
Immunoblot (IB)
(A 1:1000 dilution was sufficient for detection of TNFRSF18 in 10 ug of Mouse skeletal muscle by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.)
Related Product Information for anti-TNFRSF18 antibody
TNFRSF18 is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells (1), and could be a suitable molecular target for preventing or treating automimmune diseases (2).
Product Categories/Family for anti-TNFRSF18 antibody
References
1. "Entrez Gene: TNFRSF18 tumor necrosis factor receptor superfamily, member 18". 2. Shimizu J. et al., (2002) Nat. Immunol. 3(2): 135-142.
NCBI and Uniprot Product Information
NCBI GeneID
NCBI Official Synonym Full Names
TNF receptor superfamily member 18
NCBI Official Symbol
TNFRSF18
NCBI Official Synonym Symbols
AITR; GITR; CD357; GITR-D
NCBI Protein Information
tumor necrosis factor receptor superfamily member 18
Protein Family
NCBI Description
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
Research Articles on TNFRSF18
1. HTLV-1 infection can modify the expression of main functional transcription factors, FOXP3 and GITR
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Product Notes
The TNFRSF18 (Catalog #AAA8001960) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TNFRSF18 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TNFRSF18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000. Researchers should empirically determine the suitability of the TNFRSF18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFRSF18, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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