Mouse anti-Human TNFAIP8 Monoclonal Antibody | anti-TNFAIP8 antibody
Anti-TNFAIP8 Antibody, Mouse Monoclonal
Gene Names
TNFAIP8; GG2-1; SCCS2; SCC-S2; MDC-3.13
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
TNFAIP8; Monoclonal Antibody; Anti-TNFAIP8 Antibody; Mouse Monoclonal; TNFAIP8 Antibody; Mouse MAb; tumor necrosis factor; alpha-induced protein 8; Anti-GG2-1 Antibody; Anti-MDC-3.13 Antibody; Anti-NDED Antibody; Anti-SCC-S2 Antibody; Anti-SCCS2 Antibody; anti-TNFAIP8 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG2a
Clone Number
04
Specificity
Human TNFAIP8
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-TNFAIP8 antibody
ELISA (EIA)
Application Notes
ELISA: 1:1000-1:2000
Immunogen
Recombinant Human TNFAIP8 Protein
Conjugation
Unconjugated
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNFAIP8 (rh TNFAIP8). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-TNFAIP8 antibody
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-alpha inducible anti-apoptotic protein with multiple roles in tumor growth and survival. by the creation of cellular autophagy events, TNFAIP8 promotes cell survival and drug resistance in prostate cancer cells. TNFAIP8 regulates Hippo pathway through interacting with LATS1 to promote cell proliferation and invasion in lung cancer. TNFAIP8 may serve as a candidate biomarker for poor prognosis and a target for new therapies.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,003 Da
NCBI Official Full Name
tumor necrosis factor alpha-induced protein 8 isoform b
NCBI Official Synonym Full Names
tumor necrosis factor, alpha-induced protein 8
NCBI Official Symbol
TNFAIP8
NCBI Official Synonym Symbols
GG2-1; SCCS2; SCC-S2; MDC-3.13
NCBI Protein Information
tumor necrosis factor alpha-induced protein 8; NDED; TNF-induced protein GG2-1; TNF alpha-induced protein 8; NF-kappa-B-inducible DED-containing protein; head and neck tumor and metastasis-related protein
UniProt Protein Name
Tumor necrosis factor alpha-induced protein 8
Protein Family
UniProt Gene Name
TNFAIP8
UniProt Synonym Gene Names
TNF alpha-induced protein 8; NDED
UniProt Entry Name
TFIP8_HUMAN
Uniprot Description
TNFAIP8: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 5q23.1
Cellular Component: cytoplasm
Molecular Function: caspase inhibitor activity
Biological Process: defense response to Gram-positive bacterium; interleukin-1 beta production; negative regulation of caspase activity; negative regulation of apoptosis
Research Articles on TNFAIP8
Similar Products
Product Notes
The TNFAIP8 tnfaip8 (Catalog #AAA8107398) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-TNFAIP8 Antibody, Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNFAIP8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:1000-1:2000. Researchers should empirically determine the suitability of the TNFAIP8 tnfaip8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFAIP8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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