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Mouse TNF-RI Monoclonal Antibody | anti-TNFRSF1A antibody

TNF-RI, Human, mAb MR1-2, biotinylated

Reactivity
Human, Cynomolgus monkey, Rhesus monkey
Applications
Flow Cytometry, Functional Assay
Synonyms
TNF-RI; Monoclonal Antibody; Human; mAb MR1-2; biotinylated; Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor type I; Gene name: TNFRSF1A; TNF-RI Human mAb MR1-2 Biotin 50ug; anti-TNFRSF1A antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Cynomolgus monkey, Rhesus monkey
Clonality
Monoclonal
Isotype
IgG1
Form/Format
0.5ml (100ug/ml) 0.2um filtered protein G purified biotinylated antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
Applicable Applications for anti-TNFRSF1A antibody
Flow Cytometry (FC/FACS), Functional Studies (FS)
Immunogen
Extracellular part of TNF-R55
Conjugation
Biotin
Positive Control
Human lymphnodes or PHA activated T cells
Preparation and Storage
Product should be stored at 4 degree C.
Under recommended storage conditions, product is stable for one year.
Related Product Information for anti-TNFRSF1A antibody
The antibody reacts with the extra-cellular part of the TNF-RI. It also reacts with the soluble receptor. TNF-RI is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha: Induction of cytotoxicity and other functions are mediated largely via TNF-RI. The antibody cross reacts with rhesus and cynomolgus natural TNF-RI.
Product Categories/Family for anti-TNFRSF1A antibody
References
1. Leeuwenberg, JFM et al; Slow release of soluble TNF-Receptors by monocytes in vitro. J Immunol 1994, 152: 4036
2. Leeuwenberg, JFM et al; Lipopolysaccharide LPS-mediated soluble TNF-Receptor release and TNF-Receptor expression by monocytes; role of CD14, LPS binding protein and bactericidal/permeability-increasing protein. J Immnol 1994, 152: 5070
3. Marchetti, L et al; Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway. J Biol Chem 2004, 279: 32869

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Product Notes

The TNFRSF1A (Catalog #AAA584857) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TNF-RI, Human, mAb MR1-2, biotinylated reacts with Human, Cynomolgus monkey, Rhesus monkey and may cross-react with other species as described in the data sheet. AAA Biotech's TNF-RI can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Functional Studies (FS). Researchers should empirically determine the suitability of the TNFRSF1A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNF-RI, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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