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ELISA (EIA) (Figure 1. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human TIGIT, His tagged protein can bind Anti-TIGIT Neutralizing antibody in a linear range of 1.6-200.0 ng/ml.)

Human anti-Human TIGIT Monoclonal Antibody | anti-TIGIT antibody

Anti-TIGIT (vibostolimab biosimilar) mAb

Gene Names
TIGIT; VSIG9; VSTM3; WUCAM
Reactivity
Human
Applications
ELISA
Purity
Purified from cell culture supernatant by affinity chromatography
Synonyms
TIGIT; Monoclonal Antibody; Anti-TIGIT (vibostolimab biosimilar) mAb; VSIG9; VSTM3; MK-7684; anti-TIGIT antibody
Ordering
For Research Use Only!
Host
Human
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Purity/Purification
Purified from cell culture supernatant by affinity chromatography
Form/Format
Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA; 0.1% Procline 300
Applicable Applications for anti-TIGIT antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-10,000
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -20 degree C (Avoid repeated freezing and thawing)
Estimated 12 months from date of dispatch

ELISA (EIA)

(Figure 1. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human TIGIT, His tagged protein can bind Anti-TIGIT Neutralizing antibody in a linear range of 1.6-200.0 ng/ml.)

ELISA (EIA) (Figure 1. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human TIGIT, His tagged protein can bind Anti-TIGIT Neutralizing antibody in a linear range of 1.6-200.0 ng/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
18,432 Da
NCBI Official Full Name
T-cell immunoreceptor with Ig and ITIM domains
NCBI Official Synonym Full Names
T cell immunoreceptor with Ig and ITIM domains
NCBI Official Symbol
TIGIT
NCBI Official Synonym Symbols
VSIG9; VSTM3; WUCAM
NCBI Protein Information
T-cell immunoreceptor with Ig and ITIM domains
UniProt Protein Name
T-cell immunoreceptor with Ig and ITIM domains
UniProt Gene Name
TIGIT
UniProt Synonym Gene Names
VSIG9; VSTM3

NCBI Description

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]

Uniprot Description

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Research Articles on TIGIT

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Product Notes

The TIGIT tigit (Catalog #AAA188594) is an Antibody produced from Human and is intended for research purposes only. The product is available for immediate purchase. The Anti-TIGIT (vibostolimab biosimilar) mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TIGIT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-10,000. Researchers should empirically determine the suitability of the TIGIT tigit for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIGIT, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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