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Western Blot (WB) (Western Blot analysis of MCF-7 cells using TBL2 Monoclonal Antibody at dilution of 1:2000)

Mouse anti-Human TBL2 Monoclonal Antibody | anti-TBL2 antibody

TBL2 Monoclonal Antibody

Gene Names
TBL2; WBSCR13; WS-betaTRP
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Thiophilic Affinity Chromatograph
Synonyms
TBL2; Monoclonal Antibody; TBL2 Monoclonal Antibody; DKFZp434N024; transducin (beta) like 2; Transducin beta like protein 2; WBSCR13; WS betaTRP; anti-TBL2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgA
Clone Number
1D5C2
Purity/Purification
Thiophilic Affinity Chromatograph
Concentration
1mg/mL (varies by lot)
Sequence Length
2183
Applicable Applications for anti-TBL2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000-1:10000
IHC: 1:50-1:500
Immunogen
Fusion Protein of TBL2
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of MCF-7 cells using TBL2 Monoclonal Antibody at dilution of 1:2000)

Western Blot (WB) (Western Blot analysis of MCF-7 cells using TBL2 Monoclonal Antibody at dilution of 1:2000)
Related Product Information for anti-TBL2 antibody
TBL2 belongs to a member of the beta-transducin protein family. This gene is commonly deleted in Williams-Beuren syndrome, a developmental disorder with multi-system manifestations caused by haploinsufficiency for contiguous genes deleted in chromosome region 7q11.23. TBL2 encodes a protein with four putative WD40 repeats, which may be involved in some intracellular signaling pathway.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Calculated Molecular Weight: 446aa; 50kDa
Observed Molecular Weight: 50kDa
NCBI Official Full Name
Homo sapiens transducin (beta)-like 2, mRNA
NCBI Official Synonym Full Names
transducin beta like 2
NCBI Official Symbol
TBL2
NCBI Official Synonym Symbols
WBSCR13; WS-betaTRP
NCBI Protein Information
transducin beta-like protein 2
UniProt Protein Name
Transducin beta-like protein 2
UniProt Gene Name
TBL2
UniProt Synonym Gene Names
WBSCR13; WS-betaTRP

NCBI Description

This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008]

Uniprot Description

TBL2: TBL2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of TBL2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: endoplasmic reticulum; integral component of endoplasmic reticulum membrane

Molecular Function: phosphoprotein binding; protein kinase binding; RNA binding; translation initiation factor binding

Biological Process: cellular response to glucose starvation; endoplasmic reticulum unfolded protein response

Research Articles on TBL2

Similar Products

Product Notes

The TBL2 tbl2 (Catalog #AAA2549151) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TBL2 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TBL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:10000 IHC: 1:50-1:500. Researchers should empirically determine the suitability of the TBL2 tbl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TBL2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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