Testing Data
(Human peripheral blood platelets stained with Mouse anti Human Talin)
Mouse TALIN Monoclonal Antibody | anti-TALIN antibody
MOUSE ANTI HUMAN TALIN
Purified IgG - liquid
Western Blot: Clone TA205 has also been reported to work in Western blotting.
Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/100; Application Note: Membrane permeabilisation is required for this application. MyBioSource recommends the use of Leucoperm for this purpose.
Preparation
Histology Positive Control Tissue
Shelf Life: 18 months from date of despatch.
Testing Data
(Human peripheral blood platelets stained with Mouse anti Human Talin)
Testing Data
(Human peripheral blood platelets stained with Mouse anti Human Talin)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Uniprot Description
talin 2: As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: ruffle; focal adhesion; cytoplasm; plasma membrane; synapse; fascia adherens; intercellular junction; actin cytoskeleton
Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; structural molecule activity; actin binding; insulin receptor binding
Biological Process: intercellular junction assembly; cytoskeletal anchoring; cell adhesion
Research Articles on TALIN
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Product Notes
The TALIN tln2 (Catalog #AAA219396) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TALIN can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Flow cytometry (FC/FACS)*, Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells Western Blot: Clone TA205 has also been reported to work in Western blotting. Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/100; Application Note: Membrane permeabilisation is required for this application. MyBioSource recommends the use of Leucoperm for this purpose. Researchers should empirically determine the suitability of the TALIN tln2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TALIN, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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