Mouse anti-Human Synuclein, alpha, beta Monoclonal Antibody | anti-SPTBN1 antibody
Synuclein, alpha, beta
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Dilution: Western Blot: 1:1000-1:5000
NCBI and Uniprot Product Information
NCBI Description
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
SPTBN1: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Belongs to the spectrin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2p21
Cellular Component: spectrin; protein complex; cytoplasm; nucleolus; M band; axolemma; cytosol
Molecular Function: calmodulin binding; protein binding; structural constituent of cytoskeleton; protein complex binding; phospholipid binding; ankyrin binding; actin binding
Biological Process: axon guidance; cytokinesis after mitosis; plasma membrane organization and biogenesis; actin filament capping; Golgi to plasma membrane protein transport; common-partner SMAD protein phosphorylation; SMAD protein nuclear translocation
Research Articles on SPTBN1
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Product Notes
The SPTBN1 sptbn1 (Catalog #AAA632095) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Synuclein, alpha, beta reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Synuclein, alpha, beta can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000-1:5000. Researchers should empirically determine the suitability of the SPTBN1 sptbn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Synuclein, alpha, beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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