Western Blot (WB)
()
Mouse Superoxide Dismutase 2 Monoclonal Antibody | anti-Sod2 antibody
Superoxide Dismutase 2 antibody
Gene Names
Sod2; CG8905; DmelCG8905; dSod2; dSOD2; Mito SOD; mitSOD2; Mn SOD; Mn-SOD; Mn-SOD2; mnSOD; MnSOD; MnSODII; Mn[2+]SOD; SOD; Sod-2; SOD-2; sod2; SOD2
Applications
Western Blot, ELISA
Purity
Superoxide Dismutase 2 antibody was purified by affinity chromatography.
Synonyms
Superoxide Dismutase 2; Monoclonal Antibody; Superoxide Dismutase 2 antibody; Monoclonal Superoxide Dismutase 2; Anti-Superoxide Dismutase 2; IPOA; Amyotrophic lateral sclerosis 1; ALS1; hSod1; Superoxide Dismutase-2; ALS; anti-Sod2 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
2A1.SD
Purity/Purification
Superoxide Dismutase 2 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer containing 50% glycerol. With 0.03% sodium azide added as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
217
Applicable Applications for anti-Sod2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:2000
Biological Significance
Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
Superoxide Dismutase 2 antibody was raised in Mouse using recombinant human protein purified from E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles..
Western Blot (WB)
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Western Blot (WB)
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Related Product Information for anti-Sod2 antibody
Mouse monoclonal Superoxide Dismutase 2 antibody
Product Categories/Family for anti-Sod2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
superoxide dismutase 2 (Mn), isoform A
NCBI Official Synonym Full Names
Superoxide dismutase 2 (Mn)
NCBI Official Symbol
Sod2
NCBI Official Synonym Symbols
CG8905; DmelCG8905; dSod2; dSOD2; Mito SOD; mitSOD2; Mn SOD; Mn-SOD; Mn-SOD2; mnSOD; MnSOD; MnSODII; Mn[2+]SOD; SOD; Sod-2; SOD-2; sod2; SOD2
NCBI Protein Information
CG8905 gene product from transcript CG8905-RB
Protein Family
Research Articles on Sod2
Similar Products
Product Notes
The Sod2 (Catalog #AAA834566) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Superoxide Dismutase 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:2000. Researchers should empirically determine the suitability of the Sod2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Superoxide Dismutase 2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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