Dilution Information
Rabbit STAR Monoclonal Antibody | anti-STAR antibody
STAR, RMab (EP226)
Reactivity
Human, Mouse, Rat
Synonyms
STAR; Monoclonal Antibody; RMab (EP226); cholesterol trafficker; mitochondrial steroid acute regulatory protein; StAR related lipid transfer START domain containing 1; StARD1; START domain containing 1; START domain containing protein 1; steroid acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein; steroidogenic acute regulatory protein mitochondrial; anti-STAR antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
EP226
Form/Format
Paraffin, Frozen
STAR is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
STAR is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
Synthetic peptide corresponding to residues of human Steroidogenic Acute RegulatoryProtein (STAR) protein.
Control
Leydig Cells of Testis, Adrenal & Leydig Cell Tumors
Localization
Cytoplasmic, Membranous
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(STAR Antibody Immunohistochemistry on an FFPE Adrenal Tissue)
Immunohistochemistry (IHC)
(STAR Antibody Immunohistochemistry on an FFPE Adrenal Tissue)
Related Product Information for anti-STAR antibody
Steroidogenic acute regulatory protein (STAR) is a protein that in humans is encoded by the STAR gene. The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane.
STAR is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Low level of STAR expression in other tissues that produce steroid hormones for local use have been reported. STAR antibody is a sensitive and specific marker for Leydig cell tumor. It is useful for differential identification of sex-cord stromal tumor (SCST). Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH.
STAR is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Low level of STAR expression in other tissues that produce steroid hormones for local use have been reported. STAR antibody is a sensitive and specific marker for Leydig cell tumor. It is useful for differential identification of sex-cord stromal tumor (SCST). Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH.
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Product Notes
The STAR (Catalog #AAA370444) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STAR, RMab (EP226) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "STAR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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