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Immunohistochemistry (IHC) (Anti-Somatostatin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:20.)

Rat SST / Somatostatin Monoclonal Antibody | anti-SST antibody

Rat Monoclonal [clone YC7] (IgG2b) to Human SST / Somatostatin

Gene Names
SST; SMST
Reactivity
Guinea pig, Human, Mouse, Pig, Rat
Applications
Immunohistochemistry
Synonyms
SST / Somatostatin; Monoclonal Antibody; Rat Monoclonal [clone YC7] (IgG2b) to Human SST / Somatostatin; Anti-SST / Somatostatin Antibody (clone YC7) IHC-plus; SST; Somatostatin-28; SMST; Somatostatin-14; Somatostatin; Human SST; anti-SST antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Guinea pig, Human, Mouse, Pig, Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
YC7
Specificity
Specific for somatostatin. A hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino acid and 28 amino acid forms, produced by alternate cleavage of the gene product. This antibody does not cross react with enkephalins, other endorphins, substance P, or CGRP. It partially Reacts with somatostatin fragments. The epitope recognized by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin
Form/Format
Tissue Culture Supernatant, 0.05% Thimerosal.
Sequence Length
116
Applicable Applications for anti-SST antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen)
Application Notes
IHC-Fr, IHC-P (1:20)
Target Species
Human
Immunogen Description
Somatostatin conjugated to Thyroglobulin.
Immunogen
SST / Somatostatin antibody was raised against somatostatin conjugated to Thyroglobulin.
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.

Immunohistochemistry (IHC)

(Anti-Somatostatin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:20.)

Immunohistochemistry (IHC) (Anti-Somatostatin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:20.)
Product Categories/Family for anti-SST antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,736 Da
NCBI Official Full Name
somatostatin preproprotein
NCBI Official Synonym Full Names
somatostatin
NCBI Official Symbol
SST
NCBI Official Synonym Symbols
SMST
NCBI Protein Information
somatostatin; somatostatin-14; somatostatin-28; prepro-somatostatin; growth hormone release-inhibiting factor
UniProt Protein Name
Somatostatin
Protein Family
UniProt Gene Name
SST
UniProt Entry Name
SMS_HUMAN

NCBI Description

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

Uniprot Description

SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family.

Protein type: Secreted, signal peptide; Hormone; Secreted

Chromosomal Location of Human Ortholog: 3q28

Cellular Component: extracellular space; cell soma; extracellular region

Molecular Function: hormone activity

Biological Process: response to drug; induction of apoptosis by hormones; response to amino acid stimulus; regulation of cell migration; G-protein coupled receptor protein signaling pathway; synaptic transmission; negative regulation of cell proliferation; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; response to steroid hormone stimulus; response to heat; digestion; response to nutrient

Research Articles on SST

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Product Notes

The SST sst (Catalog #AAA246055) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Rat Monoclonal [clone YC7] (IgG2b) to Human SST / Somatostatin reacts with Guinea pig, Human, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SST / Somatostatin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin; IHC - Frozen). IHC-Fr, IHC-P (1:20). Researchers should empirically determine the suitability of the SST sst for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SST / Somatostatin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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