Mouse anti-Human SLC44A2 / CTL2 Monoclonal Antibody | anti-SLC44A2 antibody

Mouse Monoclonal [clone 3D11] (IgG1,k) to Human SLC44A2 / CTL2

Cat. Num. AAA246684

• Gene Names: SLC44A2; CTL2; PP1292
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Protein A Purified
• Synonyms: SLC44A2 / CTL2; Monoclonal Antibody; Mouse Monoclonal [clone 3D11] (IgG1; k) to Human SLC44A2 / CTL2; Anti-SLC44A2 / CTL2 Antibody (clone 3D11) IHC-plus; SLC44A2; CTL2; PP1292; Human SLC44A2; anti-SLC44A2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 3D11
• Purity/Purification: Protein A Purified
• Form/Format: PBS, pH 7.4. Sourced in Ascites.
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 706

• Applicable Applications for anti-SLC44A2 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IHC-P (10 ug/ml), WB; Usage: Tested in Western blot using the recombinant protein immunogen as the protein source. Sandwich ELISA (Recombinant protein).
• Target Species: Human
• Immunogen Description: CTL2 (AAH40556, 123 a.a. ~ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Immunogen Type: Recombinant protein
• Immunogen: SLC44A2 / CTL2 antibody was raised against cTL2 (AAH40556, 123 a.a. ~ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Preparation and Storage: Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Anti-SLC44A2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC)

(Anti-SLC44A2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC)

(Anti-SLC44A2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

ELISA (EIA)

(Detection limit for recombinant GST tagged SLC44A2 is approximately 0.3 ng/ml as a capture antibody.)

Product Categories/Family for anti-SLC44A2 antibody

Family: Transporter; Subfamily: Choline transporter-like

NCBI and Uniprot Product Information

• NCBI GI #: 222831612
• NCBI GeneID: 57153
• NCBI Accession #: NP_065161.3
• NCBI GenBank Nucleotide #: NM_020428.3
• UniProt Accession #: Q8IWA5; Q658V1; Q658Z2; Q6PJV7; Q8N2F0; Q9NY68; B2RBB1; B3KNH3; B4DFJ0; F2Q9D7
• Molecular Weight: 79,846 Da
• NCBI Official Full Name: choline transporter-like protein 2 isoform 1
• NCBI Official Synonym Full Names: solute carrier family 44 (choline transporter), member 2
• NCBI Official Symbol: SLC44A2
• NCBI Official Synonym Symbols: CTL2; PP1292
• NCBI Protein Information: choline transporter-like protein 2; solute carrier family 44, member 2
• UniProt Protein Name: Choline transporter-like protein 2
• Protein Family: Choline transporter-like protein
• UniProt Gene Name: SLC44A2
• UniProt Synonym Gene Names: CTL2
• UniProt Entry Name: CTL2_HUMAN

Uniprot Description

SLC44A2: Isoform 1, but not isoform 3, exhibits some choline transporter activity. Belongs to the CTL (choline transporter-like) family. 3 isoforms of the human protein are produced by alternative promoter.

Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: lysosomal membrane; integral to membrane; plasma membrane

Molecular Function: signal transducer activity; choline transmembrane transporter activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylcholine biosynthetic process; choline transport; signal transduction; transmembrane transport