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Immunohistochemistry (IHC) (Immunohistochemical staining of SERT in rat brain using S1001-28. The antibody reacts with fibers in cerebral cortex (cingulate cortex in the image) and other brain regions innervated by serotonin fibers, as well as with cell bodies in the brainstem raphe (inset).)

Mouse anti-Mouse, Rat Serotonin Transporter Monoclonal Antibody | anti-SERT antibody

Serotonin Transporter (SERT, 5HT, 5-hydroxytryptamine) (HRP)

Reactivity
Mouse, Rat
Applications
Immunohistochemistry
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Serotonin Transporter; Monoclonal Antibody; Serotonin Transporter (SERT; 5HT; 5-hydroxytryptamine) (HRP); anti-SERT antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2Q115
Specificity
Recognizes Serotonin Transporter. Species Crossreactivity: Rat and mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Applicable Applications for anti-SERT antibody
Immunohistochemistry (IHC)
Immunogen
Rat serotonin transporter, N-terminus/GST fusion protein (aa1-85).
Conjugate
HRP
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(Immunohistochemical staining of SERT in rat brain using S1001-28. The antibody reacts with fibers in cerebral cortex (cingulate cortex in the image) and other brain regions innervated by serotonin fibers, as well as with cell bodies in the brainstem raphe (inset).)

Immunohistochemistry (IHC) (Immunohistochemical staining of SERT in rat brain using S1001-28. The antibody reacts with fibers in cerebral cortex (cingulate cortex in the image) and other brain regions innervated by serotonin fibers, as well as with cell bodies in the brainstem raphe (inset).)
Product Categories/Family for anti-SERT antibody
References
1. Molecular and Cellular Neuroscience (1997) 9:170-184. 2. Inazu, M. et al., Neurochemistry International (2001) 39:39-49.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
70,172 Da
NCBI Official Full Name
Sodium-dependent serotonin transporter
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter), member 4
NCBI Official Symbol
Slc6a4
NCBI Protein Information
sodium-dependent serotonin transporter; 5HTT; 5HT transporter; solute carrier family 6, member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hyd
UniProt Protein Name
Sodium-dependent serotonin transporter
UniProt Gene Name
Slc6a4
UniProt Synonym Gene Names
5HTT
UniProt Entry Name
SC6A4_RAT

NCBI Description

binds serotonin; may play a role in regulation of motor activity [RGD, Feb 2006]

Uniprot Description

Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.

Research Articles on SERT

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Product Notes

The SERT slc6a4 (Catalog #AAA6243925) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Serotonin Transporter (SERT, 5HT, 5-hydroxytryptamine) (HRP) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Serotonin Transporter can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SERT slc6a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Serotonin Transporter, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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