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Mouse anti-Human Serine Hydroxymethyltransferase 1 Monoclonal Antibody | anti-SHMT1 antibody

Mouse Anti Human Serine Hydroxymethyltransferase 1

Gene Names
SHM1; F20D10.50; F20D10_50; SERINE HYDROXYMETHYLTRANSFERASE 1; SERINE TRANSHYDROXYMETHYLASE; SERINE TRANSHYDROXYMETHYLTRANSFERASE; serine transhydroxymethyltransferase 1; SHMT1; STM
Reactivity
Human
Applications
ELISA, Western Blot, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence
Purity
Antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Synonyms
Serine Hydroxymethyltransferase 1; Monoclonal Antibody; Mouse Anti Human Serine Hydroxymethyltransferase 1; SHMT1 Antibody; Serine hydroxymethyltransferase 1 (soluble); CSHMT; Glycine hydroxymethyltransferase; Serine methylase; 14 kDa protein; cytoplasmic serine hydroxymethyltransferase; serine hydroxymethyltransferase cytosolic; EC 2.1.2.1; Mouse Anti Human; anti-SHMT1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 heavy chain and k light chain.
Clone Number
PAT26E5AT
Purity/Purification
Antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Form/Format
Sterile filtered colorless solution.
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sequence Length
517
Applicable Applications for anti-SHMT1 antibody
ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
Immunogen
Anti-human SHMT1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SHMT1 amino acids 1-483 purified from E Coli.
Preparation and Storage
12 months at -20 degree C. 1 month at 4 degree C.
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
Related Product Information for anti-SHMT1 antibody
SHMT1 is a member of the SHMT family. SHMT1 is the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme which catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5 10-methylene tetrahydrofolate. In addition, SHMT1 specifically provides one-carbon units for thymidylate biosynthesis, reduces methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate and inhibits SAM synthesis.
Product Categories/Family for anti-SHMT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,401 Da
NCBI Official Full Name
serine transhydroxymethyltransferase 1
NCBI Official Symbol
SHM1
NCBI Official Synonym Symbols
F20D10.50; F20D10_50; SERINE HYDROXYMETHYLTRANSFERASE 1; SERINE TRANSHYDROXYMETHYLASE; SERINE TRANSHYDROXYMETHYLTRANSFERASE; serine transhydroxymethyltransferase 1; SHMT1; STM
NCBI Protein Information
serine transhydroxymethyltransferase 1
UniProt Protein Name
Serine hydroxymethyltransferase 1, mitochondrial
UniProt Gene Name
SHM1
UniProt Synonym Gene Names
SHMT1; STM; AtSHMT1; STM

NCBI Description

Encodes a protein with mitochondrial serine hydroxymethyltransferase activity, which functions in the photorespiratory pathway, catalyzes the conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Involved in controlling cell damage caused by abiotic stress, such as high light and salt and the hypersensitive defense response of plants.

Uniprot Description

Functions in the photorespiratory pathway in catalyzing the interconversion of serine and glycine. Involved in controlling cell damage caused by abiotic stress, such as high light and salt and the hypersensitive defense response of plants.

Research Articles on SHMT1

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Product Notes

The SHMT1 shm1 (Catalog #AAA146671) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human Serine Hydroxymethyltransferase 1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Serine Hydroxymethyltransferase 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the SHMT1 shm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Serine Hydroxymethyltransferase 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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