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Western Blot (WB) (Western blot detection of Septin 8 in CHO-K1,C6 cell lysates using Septin 8 Rabbit mAb(1:1000 diluted). Predicted band size:56kDa. Observed band size:56kDa.)

Rabbit Septin 8 Monoclonal Antibody | anti-SEPT8 antibody

Septin 8 Rabbit mAb

Gene Names
SEPT8; SEP2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, Immunoprecipitation
Purity
Affinity purified
Synonyms
Septin 8; Monoclonal Antibody; Septin 8 Rabbit mAb; SEP2; SEPT8; anti-SEPT8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
50nM Tris-Glycine (pH7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Applicable Applications for anti-SEPT8 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
Application Notes
WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Immunogen
A synthetic peptide of human Septin 8
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot detection of Septin 8 in CHO-K1,C6 cell lysates using Septin 8 Rabbit mAb(1:1000 diluted). Predicted band size:56kDa. Observed band size:56kDa.)

Western Blot (WB) (Western blot detection of Septin 8 in CHO-K1,C6 cell lysates using Septin 8 Rabbit mAb(1:1000 diluted). Predicted band size:56kDa. Observed band size:56kDa.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
483
NCBI Official Full Name
Septin-8
NCBI Official Synonym Full Names
septin 8
NCBI Official Symbol
SEPT8
NCBI Official Synonym Symbols
SEP2
NCBI Protein Information
septin-8
UniProt Protein Name
Septin-8
UniProt Gene Name
SEPT8
UniProt Synonym Gene Names
KIAA0202
UniProt Entry Name
SEPT8_HUMAN

NCBI Description

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Uniprot Description

SEPT8: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. Belongs to the septin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Hydrolase

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: cytoskeleton; cytoplasm

Molecular Function: protein binding; GTP binding

Biological Process: cell cycle

Research Articles on SEPT8

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Product Notes

The SEPT8 sept8 (Catalog #AAA4753439) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Septin 8 Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Septin 8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP). WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20 IP: 1:20. Researchers should empirically determine the suitability of the SEPT8 sept8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Septin 8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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