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ELISA (ELISA Black line: Control Antigen (100 ng); Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng))

Mouse anti-Human SEC31A Monoclonal Antibody | anti-SEC31A antibody

Mouse Monoclonal Antibody to SEC31A

Gene Names
SEC31A; ABP125; ABP130; HSPC275; HSPC334; SEC31L1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Synonyms
SEC31A; Monoclonal Antibody; Mouse Monoclonal Antibody to SEC31A; ABP125; ABP130; HSPC275; HSPC334; SEC31L1; anti-SEC31A antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5D12C6
Form/Format
Purified antibody in PBS with 0.05% sodium azide
Sequence Length
129
Applicable Applications for anti-SEC31A antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1/10000
IHC-P: 1/200-1/1000
WB: 1/500-1/2000.
Immunogen
Purified recombinant fragment of human SEC31A (AA: 429-571) expressed in E. Coli.

ELISA

(ELISA Black line: Control Antigen (100 ng); Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng))

ELISA (ELISA Black line: Control Antigen (100 ng); Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng))

Western blot (WB)

(Analysis using SEC31A mAb against human SEC31A recombinant protein. (Expected MW is 41.8 kDa))

Western blot (WB) (Analysis using SEC31A mAb against human SEC31A recombinant protein. (Expected MW is 41.8 kDa))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
133kDa
NCBI Official Full Name
SEC31A, partial
NCBI Official Synonym Full Names
SEC31 homolog A, COPII coat complex component
NCBI Official Symbol
SEC31A
NCBI Official Synonym Symbols
ABP125; ABP130; HSPC275; HSPC334; SEC31L1
NCBI Protein Information
protein transport protein Sec31A
UniProt Protein Name
Protein transport protein Sec31A
Protein Family
UniProt Gene Name
SEC31A
UniProt Synonym Gene Names
KIAA0905; SEC31L1

NCBI Description

The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Uniprot Description

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (PubMed:10788476). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules ().

Research Articles on SEC31A

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Product Notes

The SEC31A sec31a (Catalog #AAA8528485) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal Antibody to SEC31A reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SEC31A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1/10000 IHC-P: 1/200-1/1000 WB: 1/500-1/2000. Researchers should empirically determine the suitability of the SEC31A sec31a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEC31A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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