Mouse SDR16C5 Monoclonal Antibody | anti-SDR16C5 antibody

SDR16C5 (Short-chain Dehydrogenase/reductase Family 16C Member 5, Epidermal Retinol Dehydrogenase 2, EPHD-2, RDHE2, RDH-E2, RDH#2, Retinal Short-chain Dehydrogenase Reductase 2, RetSDR2) (FITC)

Cat. Num. AAA6149284

• Gene Names: SDR16C5; RDH#2; RDHE2; EPHD-2; RDH-E2; retSDR2
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SDR16C5; Monoclonal Antibody; SDR16C5 (Short-chain Dehydrogenase/reductase Family 16C Member 5; Epidermal Retinol Dehydrogenase 2; EPHD-2; RDHE2; RDH-E2; RDH#2; Retinal Short-chain Dehydrogenase Reductase 2; RetSDR2) (FITC); EC=1.1.1.105; anti-SDR16C5 antibody

• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 3G8
• Specificity: Recognizes human RDHE2. Species Crossreactivity: mouse and rat.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
• Sequence Length: 2509

• Applicable Applications for anti-SDR16C5 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant protein corresponding to aa26-310 from human RDHE2 (AAH37219) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKTGMFEGCTTGCPSLLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKSFLPLKTGLLIADYLGILHAMDGFVDQKKKL
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(RDHE2 monoclonal antibody. Western Blot analysis of RDHE2 expression in PC-12.)

Western Blot (WB)

(RDHE2 monoclonal antibody, Western Blot analysis of RDHE2 expression in Hela NE.)

Western Blot (WB)

(RDHE2 monoclonal antibody. Western Blot analysis of RDHE2 expression in Raw 264.7.)

Western Blot (WB)

(RDHE2 monoclonal antibody. Western Blot analysis of RDHE2 expression in NIH/3T3.)

Western Blot (WB)

(Western Blot analysis of SDR16C5 expression in transfected 293T cell line by RDHE2 monoclonal antibody (M01). Lane 1: SDR16C5 transfected lysate (34.1kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-SDR16C5 antibody

Antibodies; Enzymes; Dehydrogenase

NCBI and Uniprot Product Information

• NCBI GI #: 22713433
• NCBI GeneID: 195814
• NCBI Official Full Name: Homo sapiens short chain dehydrogenase/reductase family 16C, member 5, mRNA
• NCBI Official Synonym Full Names: short chain dehydrogenase/reductase family 16C member 5
• NCBI Official Symbol: SDR16C5
• NCBI Official Synonym Symbols: RDH#2; RDHE2; EPHD-2; RDH-E2; retSDR2
• NCBI Protein Information: epidermal retinol dehydrogenase 2
• Protein Family: Epidermal retinol dehydrogenase

NCBI Description

This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD(+)/NADH as cofactors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]