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Western Blot (WB) (Western blot analysis using SDC1 mAb against human SDC1 (AA)

Mouse anti-Human, Mouse SDC1 Monoclonal Antibody | anti-SDC1 antibody

Anti-SDC1 Mouse mAb

Gene Names
SDC1; SDC; CD138; SYND1; syndecan
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry, Functional Assay
Synonyms
SDC1; Monoclonal Antibody; Anti-SDC1 Mouse mAb; SDC; CD138; SYND1; syndecan; anti-SDC1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1A3H4
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Sequence Length
310
Applicable Applications for anti-SDC1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
Immunogen
Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E Coli.

Western Blot (WB)

(Western blot analysis using SDC1 mAb against human SDC1 (AA)

Western Blot (WB) (Western blot analysis using SDC1 mAb against human SDC1 (AA)

Western Blot (WB)

(Western blot analysis using SDC1 mAb against HEK293 (1) and SDC1 (AA)

Western Blot (WB) (Western blot analysis using SDC1 mAb against HEK293 (1) and SDC1 (AA)

Western Blot (WB)

(Western blot analysis using SDC1 mouse mAb against MCF-7 (1), Hela (2), HepG2 (3), T47D (4), SW620 (5), Jurkat (6) and NIH/3T3 (7) cell lysate.)

Western Blot (WB) (Western blot analysis using SDC1 mouse mAb against MCF-7 (1), Hela (2), HepG2 (3), T47D (4), SW620 (5), Jurkat (6) and NIH/3T3 (7) cell lysate.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HepG2 cells using SDC1 mouse mAb (green). Blue)

Immunofluorescence (IF) (Immunofluorescence analysis of HepG2 cells using SDC1 mouse mAb (green). Blue)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of HepG2 cells using SDC1 mouse mAb (green) and negative control (red).)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of HepG2 cells using SDC1 mouse mAb (green) and negative control (red).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SDC1 mouse mAb with DAB staining.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SDC1 mouse mAb with DAB staining.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using SDC1 mouse mAb with DAB staining.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using SDC1 mouse mAb with DAB staining.)
Related Product Information for anti-SDC1 antibody
Entrez Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32.5
NCBI Official Full Name
syndecan-1
NCBI Official Synonym Full Names
syndecan 1
NCBI Official Symbol
SDC1
NCBI Official Synonym Symbols
SDC; CD138; SYND1; syndecan
NCBI Protein Information
syndecan-1
UniProt Protein Name
Syndecan-1
Protein Family
UniProt Gene Name
SDC1
UniProt Synonym Gene Names
SDC; SYND1

NCBI Description

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

Uniprot Description

syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family.

Protein type: Extracellular matrix; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: cell surface; cytoplasm; focal adhesion; Golgi lumen; integral to plasma membrane; lysosomal lumen; plasma membrane

Molecular Function: protein binding; protein C-terminus binding

Biological Process: cell migration; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; lipoprotein metabolic process; myoblast development; retinoid metabolic process; striated muscle cell development

Research Articles on SDC1

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Product Notes

The SDC1 sdc1 (Catalog #AAA476508) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-SDC1 Mouse mAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SDC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the SDC1 sdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SDC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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