Immunohistochemistry - Paraffin (IHC)
(Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
Mouse anti-Human SAMHD1 Monoclonal Antibody | anti-SAMHD1 antibody
Anti-SAMHD1 Antibody (clone 2D7) IHC-plus
IF (1:100)
IHC-P (10 ug/ml)
WB (1:2000)
Immunohistochemistry - Paraffin (IHC)
(Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunofluorescence (IF)
(Anti-SAMHD1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SAMHD1.)
Immunofluorescence (IF)
(Anti-SAMHD1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SAMHD1.)
Western Blot (WB)
(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SAMHD1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SAMHD1.)
Western Blot (WB)
(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SAMHD1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SAMHD1.)
Flow Cytometry (FC/FACS)
(Flow cytometry of HeLa cells, using anti-SAMHD1 antibody (Red), compared to a nonspecific negative control antibody (Blue).)
Flow Cytometry (FC/FACS)
(Flow cytometry of HeLa cells, using anti-SAMHD1 antibody (Red), compared to a nonspecific negative control antibody (Blue).)
Flow Cytometry (FC/FACS)
(Flow cytometry of Jurkat cells, using anti-SAMHD1 antibody (Red), compared to a nonspecific negative control antibody (Blue).)
Flow Cytometry (FC/FACS)
(Flow cytometry of Jurkat cells, using anti-SAMHD1 antibody (Red), compared to a nonspecific negative control antibody (Blue).)
NCBI and Uniprot Product Information
NCBI Description
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]
Uniprot Description
SAMHD1: a protein induced by interferon gamma.
Protein type: EC 3.1.4.-
Chromosomal Location of Human Ortholog: 20pter-q12
Cellular Component: intracellular; nucleoplasm; nucleus; plasma membrane
Molecular Function: dGTP binding; dGTPase activity; nucleic acid binding; protein binding; RNA binding; zinc ion binding
Biological Process: cytokine and chemokine mediated signaling pathway; dATP catabolic process; defense response to virus; dGTP catabolic process; immune response; protein homotetramerization; regulation of innate immune response
Disease: Aicardi-goutieres Syndrome 5; Chilblain Lupus 2
Research Articles on SAMHD1
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Product Notes
The SAMHD1 samhd1 (Catalog #AAA249336) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-SAMHD1 Antibody (clone 2D7) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SAMHD1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS). Flow Cytometry (1:100) IF (1:100) IHC-P (10 ug/ml) WB (1:2000). Researchers should empirically determine the suitability of the SAMHD1 samhd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SAMHD1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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