Western Blot (WB)
(Western Blot analysis of A549 cells using RXRG Monoclonal Antibody at dilution of 1:2000)
Mouse anti-Human RXRG Monoclonal Antibody | anti-RXRG antibody
RXRG Monoclonal Antibody
Western Blot (WB)
(Western Blot analysis of A549 cells using RXRG Monoclonal Antibody at dilution of 1:2000)
Western Blot (WB)
(Western Blot analysis of A549 cells using RXRG Monoclonal Antibody at dilution of 1:2000)
NCBI and Uniprot Product Information
Observed Molecular Weight: 52kDa
NCBI Description
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
Uniprot Description
RXRG: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Belongs to the nuclear hormone receptor family. NR2 subfamily.
Protein type: DNA-binding; Nuclear receptor
Chromosomal Location of Human Ortholog: 1q23.3
Cellular Component: nucleoplasm
Molecular Function: 9-cis retinoic acid receptor activity; protein binding; steroid hormone receptor activity; zinc ion binding
Biological Process: protein homotetramerization; retinoic acid receptor signaling pathway; steroid hormone mediated signaling; transcription initiation from RNA polymerase II promoter
Research Articles on RXRG
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Product Notes
The RXRG rxrg (Catalog #AAA2549132) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RXRG Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RXRG can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-1:10000. Researchers should empirically determine the suitability of the RXRG rxrg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RXRG, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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