Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human brain, cerebellum tissue stained with rSec8, mAb (14G1) at 5µg/ml.)
Mouse rSec8 Monoclonal Antibody | anti-rSec8 antibody
rSec8 monoclonal antibody (14G1)
Detects a band of ~110kDa by Western blot.
Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human brain, cerebellum tissue stained with rSec8, mAb (14G1) at 5µg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human brain, cerebellum tissue stained with rSec8, mAb (14G1) at 5µg/ml.)
Western Blot (WB)
(Western blot analysis of rSec8: Lane 1: MWM, Lane 2: Brain (rat), (tissue extract), Lane 3: Brain (mouse), (tissue extract), Lane 4: MDBK Cell Lysate.)
Western Blot (WB)
(Western blot analysis of rSec8: Lane 1: MWM, Lane 2: Brain (rat), (tissue extract), Lane 3: Brain (mouse), (tissue extract), Lane 4: MDBK Cell Lysate.)
NCBI and Uniprot Product Information
NCBI Description
involved in Golgi-to-plasma membrane vesicle trafficking [RGD, Feb 2006]
Uniprot Description
EXOC4: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC8 family.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 4q22
Cellular Component: cell soma; cytoplasm; dendritic shaft; endosome; exocyst; Golgi apparatus; growth cone; membrane; microvillus; myelin sheath; neuron projection; postsynaptic density; protein complex; synapse
Molecular Function: PDZ domain binding; protein binding; protein complex binding; protein N-terminus binding; Ral GTPase binding
Biological Process: establishment of cell polarity; Golgi to transport vesicle transport; oligodendrocyte differentiation; paraxial mesoderm formation; positive regulation of calcium-mediated signaling; protein targeting to membrane; regulation of protein transport; synaptic transmission; vesicle targeting
Research Articles on rSec8
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Product Notes
The rSec8 exoc4 (Catalog #AAA565749) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The rSec8 monoclonal antibody (14G1) reacts with Human, Mouse, Rat, Sheep, Dog, Pig, Monkey, Bovine, Chicken, Fish, Guinea pig, Hamster, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's rSec8 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB). Immunoprecipitation (12.5ug/ml), Western Blot (1:1'000, colorimetric). Detects a band of ~110kDa by Western blot. Researchers should empirically determine the suitability of the rSec8 exoc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "rSec8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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