Mouse Rotavirus, Capsid Protein Monoclonal Antibody
Rotavirus, Capsid Protein
Reactivity
Bovine, Human
Applications
ELISA, Immunofluorescence
Purity
Highly PurifiedPurified by DEAE chromatography.
Synonyms
Rotavirus; Capsid Protein; Monoclonal Antibody; Anti -Rotavirus; anti-Rotavirus; Capsid Protein antibody
Host
Mouse
Reactivity
Bovine, Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
9L629
Specificity
Recognizes rotavirus on bovine and human feces or infected cells. Recognizes the 41kD capsid major protein, group specific antigen.
Purity/Purification
Highly Purified
Purified by DEAE chromatography.
Purified by DEAE chromatography.
Form/Format
Supplied as a liquid in PBS (without Ca2+ and Mg2+), pH 7.2. No preservative added.
Applicable Applications for anti-Rotavirus, Capsid Protein antibody
ELISA (EL/EIA), Immunofluorescence (IF)
Application Notes
Suitable for use in Immunofluorescence and ELISA.
Immunogen
Electron microscopy characterized wild strain, isolated from calf feces.
Hybridoma
Myeloma Sp2/0-Ag14 myeloma cells with spleen cells from Balb/c mice.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Rotavirus, Capsid Protein antibody
Rotaviruses, members of the family Reoviridae, are a major cause of diarrhea in young mammals. Rotavirus infections also result in economic losses in agriculture due to diarrhea in calf, pig, sheep, and poultry rearing. Diarrhea (or scours) due to the rotavirus Nebraska Calf Diarrhea Virus can affect calves up to 30 days of age or older. Diarrhea begins 2 to 3 days after exposure. identification is by history, lesions (ulcers on the tongue, lips, and mouth) and laboratory tests. Mortality rates may be as high as 50 percent, depending on the secondary bacteria present.
Human rotaviruses, the major etiological agents of severe infantile diarrhea worldwide, display very diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection. Therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
Human rotaviruses, the major etiological agents of severe infantile diarrhea worldwide, display very diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection. Therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
Product Categories/Family for anti-Rotavirus, Capsid Protein antibody
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Product Notes
The Rotavirus, Capsid Protein (Catalog #AAA632333) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Rotavirus, Capsid Protein reacts with Bovine, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Rotavirus, Capsid Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunofluorescence (IF). Suitable for use in Immunofluorescence and ELISA. Researchers should empirically determine the suitability of the Rotavirus, Capsid Protein for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rotavirus, Capsid Protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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