Western Blot (WB)
(Western Blot detection against Immunogen (34.54kD).)
Mouse anti-Human, Rat RIMS2 Monoclonal Antibody | anti-RIMS2 antibody
RIMS2 (Regulating Synaptic Membrane Exocytosis Protein 2, Rab3-interacting Molecule 2, RIM 2, Rab-3-interacting Protein 3, KIAA0751, RAB3IP3, RIM2)
Gene Names
RIMS2; OBOE; RIM2; RAB3IP3
Reactivity
Human, Rat
Applications
ELISA, Western Blot
Purity
AscitesAscites
Synonyms
RIMS2; Monoclonal Antibody; RIMS2 (Regulating Synaptic Membrane Exocytosis Protein 2; Rab3-interacting Molecule 2; RIM 2; Rab-3-interacting Protein 3; KIAA0751; RAB3IP3; RIM2); Anti -RIMS2 (Regulating Synaptic Membrane Exocytosis Protein 2; anti-RIMS2 antibody
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Isotype
IgM,k
Clone Number
3C12
Specificity
Recognizes human RIMS2. Species Crossreactivity: rat.
Purity/Purification
Ascites
Ascites
Ascites
Form/Format
Supplied as a liquid in ascites fluid.
Sequence
LANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLPIDRPDLRRTD
Applicable Applications for anti-RIMS2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Immunogen
Partial recombinant corresponding to aa181-260 from RIMS2 (NP_055492) with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen (34.54kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (34.54kD).)
Related Product Information for anti-RIMS2 antibody
RIMS2 is a Rab effector involved in exocytosis. It may act as a scaffold protein. The mature cytomatrix at the active zone (CAZ) of the synapse is defined by a set of multidomain proteins that harbor several protein-protein or protein-lipid interaction domains. The complete protein composition of the CAZ is not known to date, but it includes the proteins RIMs, Munc13-1, ERC/CAST, Piccolo/Aczonin and Bassoon. RIMs are presynaptic active zone proteins that regulate Ca2+ triggered release of neurotransmitters.
Product Categories/Family for anti-RIMS2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
160,403 Da
NCBI Official Full Name
regulating synaptic membrane exocytosis protein 2 isoform d
NCBI Official Synonym Full Names
regulating synaptic membrane exocytosis 2
NCBI Official Symbol
RIMS2
NCBI Official Synonym Symbols
OBOE; RIM2; RAB3IP3
NCBI Protein Information
regulating synaptic membrane exocytosis protein 2; RIM 2; nuclear protein; RAB3 interacting protein 3; rab-3-interacting protein 3; rab3-interacting molecule 2; rab-3-interacting molecule 2; non-small cell lung cancer RimL3a protein; non-small cell lung cancer RimL3c protein
UniProt Protein Name
Regulating synaptic membrane exocytosis protein 2
Protein Family
UniProt Gene Name
RIMS2
UniProt Synonym Gene Names
KIAA0751; RAB3IP3; RIM2; RIM 2
UniProt Entry Name
RIMS2_HUMAN
Uniprot Description
RIMS2: Rab effector involved in exocytosis. May act as scaffold protein. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 8q22.3
Cellular Component: presynaptic membrane; presynaptic active zone; cell junction
Molecular Function: protein binding; metal ion binding; Rab GTPase binding
Biological Process: regulation of exocytosis; intracellular protein transport; cAMP-mediated signaling; regulation of membrane potential; insulin secretion; calcium ion-dependent exocytosis of neurotransmitter; calcium ion-dependent exocytosis
Research Articles on RIMS2
Similar Products
Product Notes
The RIMS2 rims2 (Catalog #AAA645537) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RIMS2 (Regulating Synaptic Membrane Exocytosis Protein 2, Rab3-interacting Molecule 2, RIM 2, Rab-3-interacting Protein 3, KIAA0751, RAB3IP3, RIM2) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RIMS2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the RIMS2 rims2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LANADLEDSR ISMLRMDRPS RQRSISERRA AMENQRSYSM ERTREAQGPS SYAQRTTNHS PPTPRRSPLP IDRPDLRRTD. It is sometimes possible for the material contained within the vial of "RIMS2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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