Western Blot (WB)
(Western Blot analysis of Human blood tissue using RBP4 Monoclonal Antibody at dilution of 1:4000)
Mouse anti-Human RBP4 Monoclonal Antibody | anti-RBP4 antibody
RBP4 Monoclonal Antibody
Gene Names
RBP4; RDCCAS; MCOPCB10
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein A purification
Synonyms
RBP4; Monoclonal Antibody; RBP4 Monoclonal Antibody; Plasma retinol binding protein; PRBP; RBP; Retinol binding protein 4;; anti-RBP4 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Purity/Purification
Protein A purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Sequence Length
201
Applicable Applications for anti-RBP4 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000-1:8000
IHC: 1:20-1:200
IHC: 1:20-1:200
Immunogen
Fusion protein of RBP4
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of Human blood tissue using RBP4 Monoclonal Antibody at dilution of 1:4000)
Western Blot (WB)
(Western Blot analysis of Human blood tissue using RBP4 Monoclonal Antibody at dilution of 1:4000)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffinembedded human liver cancer tissue slide using RBP Monoclonal Antibody at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffinembedded human liver cancer tissue slide using RBP Monoclonal Antibody at dilution of 1:50)
Related Product Information for anti-RBP4 antibody
RBP4 (retinol-binding protein 4) is a carrier protein that transports vitamin A (retinol) from the liver to the peripheral tissues. Synthesized primarily by hepatocytes and adipocytes as a 21 kDa non-glycosylated protein, RBP4 is secreted into the circulation as a retinol-RBP4 complex. In plasma the RBP4-retinol complex is bound to transthyretin (TRR), which prevents prevent kidney filtration. Two truncated forms of RBP4, RBP4-L (truncated at Leu-183) and RBP4-LL (truncated at Leu-182 and Leu-183), exist by proteolytic process. RBP4-L and RBP4-LL, which do not bind TTR, are normally excreted into the urine but accumulate in the serum during renal failure. Urinary RBP4 has been reported as marker for glomerular disease. RBP4 also was identified as an adipokine that elevated in some insulin-resistant states. Measurement of serum RBP4 could be used to assess the risk of insulin resistance, type 2 diabetes, obesity, and cardiovascular disease. (18752671, 16034410)
Product Categories/Family for anti-RBP4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 201aa, 23kDa
Observed MW: 23kDa
Observed MW: 23kDa
NCBI Official Full Name
retinol-binding protein 4 isoform a
NCBI Official Synonym Full Names
retinol binding protein 4
NCBI Official Symbol
RBP4
NCBI Official Synonym Symbols
RDCCAS; MCOPCB10
NCBI Protein Information
retinol-binding protein 4
UniProt Protein Name
Retinol-binding protein 4
Protein Family
UniProt Gene Name
RBP4
UniProt Synonym Gene Names
PRBP; RBP
NCBI Description
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]
Uniprot Description
Retinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (PubMed:22665496).
Research Articles on RBP4
Similar Products
Product Notes
The RBP4 rbp4 (Catalog #AAA2542048) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RBP4 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RBP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:8000 IHC: 1:20-1:200 . Researchers should empirically determine the suitability of the RBP4 rbp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBP4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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