Mouse anti-Human, Mouse RAC2 Monoclonal Antibody | anti-RAC2 antibody

RAC2 Monoclonal Antibody

Cat. Num. AAA2542044

• Gene Names: RAC2; Gx; EN-7; HSPC022; p21-Rac2
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry, ELISA
• Purity: Store at -20 degree C. Avoid freeze/thaw cycles.
• Synonyms: RAC2; Monoclonal Antibody; RAC2 Monoclonal Antibody; EN 7; EN-7; EN7; GX; HSPC 022; HSPC022; p21 Rac 2; p21 Rac2; p21-Rac2; p21Rac2; RAC 2; Rac2; Ras related C3 botulinum toxin substrate 2 (rho family; small GTP binding protein Rac2; Ras related C3 botulinum toxin substrate 2; Ras related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac2); Ras related C3 botulinum toxin substrate 3; Ras-related C3 botulinum toxin substrate 2; Rho family small GTP binding protein Rac 2; Rho family small GTP binding protein Rac2; Small G protein; anti-RAC2 antibody

• Host: Mouse
• Reactivity: Human, Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Purity/Purification: Store at -20 degree C. Avoid freeze/thaw cycles.
• Form/Format: PBS with 0.1% sodium azide, 50% glycerol, PH7.3
• Sequence Length: 192

• Applicable Applications for anti-RAC2 antibody: Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: WB: 1:500-1:5000; IHC: 1:20-1:200
• Immunogen: Fusion protein of RAC2
• Note: Centrifuge before opening to ensure complete recovery of vial contents.
• Preparation and Storage: Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of HL-60 cells using RAC2 Monoclonal Antibody at dilution of 1:500)

Related Product Information for anti-RAC2 antibody

RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.

Product Categories/Family for anti-RAC2 antibody

Cancer; Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 4506381
• NCBI GeneID: 5880
• NCBI Accession #: NP_002863.1
• NCBI GenBank Nucleotide #: NM_002872.4
• UniProt Accession #: P15153; Q9UDJ4
• Molecular Weight: Calculated MW: 21kDa; Observed MW: 21kDa
• NCBI Official Full Name: ras-related C3 botulinum toxin substrate 2
• NCBI Official Synonym Full Names: Rac family small GTPase 2
• NCBI Official Symbol: RAC2
• NCBI Official Synonym Symbols: Gx; EN-7; HSPC022; p21-Rac2
• NCBI Protein Information: ras-related C3 botulinum toxin substrate 2
• UniProt Protein Name: Ras-related C3 botulinum toxin substrate 2
• Protein Family: Ras-related protein
• UniProt Gene Name: RAC2

NCBI Description

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]

Uniprot Description

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.