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Western Blot (WB) ()

Mouse R Ras Monoclonal Antibody | anti-RRAS antibody

R Ras antibody

Applications
Western Blot
Purity
R Ras antibody was purified by ammonium sulfate precipitation
Synonyms
R Ras; Monoclonal Antibody; R Ras antibody; Monoclonal R Ras; Anti-R Ras; RRAS; related RAS viral (r-ras) oncogene homolog; BOS_17720; fb23a02; Harvey rat sarcoma oncogene; subgroup R; Harvey rat sarcoma virus oncogene; Oncogene RRAS; p23; ras-related protein R-Ras; Ras-related protein R-RAS (P23); anti-RRAS antibody
Ordering
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b kappa
Clone Number
6A8
Purity/Purification
R Ras antibody was purified by ammonium sulfate precipitation
Form/Format
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Sequence Length
218
Applicable Applications for anti-RRAS antibody
Western Blot (WB)
Application Notes
WB: 1:2000
Biological Significance
The Ras superfamily of small GTPases includes the Ras, Rho, Arf, Rab, and Ran families. Ras-regulated signal pathways control such as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. These GTPases function as molecular switches that control eukaryotic cell function by cycling between two interconvertible forms, a GDP-bound inactive form and a GTP-bound active form. The binding of GTP leads to a conformational change in the downstream effector-binding domain of the G-protein.
Cross-Reactivity
Human
Immunogen
R Ras antibody was raised in Mouse using a recombinant human protein purified from E Coli(His-R-Ras) as the immunogen
Preparation and Storage
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles

Western Blot (WB)

()

Western Blot (WB) ()
Related Product Information for anti-RRAS antibody
Mouse monoclonal R Ras antibody
Product Categories/Family for anti-RRAS antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
23,480 Da
NCBI Official Full Name
R-ras
NCBI Official Synonym Full Names
related RAS viral (r-ras) oncogene homolog
NCBI Official Symbol
RRAS
NCBI Protein Information
ras-related protein R-Ras
UniProt Protein Name
Ras-related protein R-Ras
Protein Family
UniProt Gene Name
RRAS
UniProt Entry Name
RRAS_HUMAN

NCBI Description

The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]

Uniprot Description

RRas: a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K.

Protein type: G protein, monomeric; Motility/polarity/chemotaxis; G protein, monomeric, Ras; G protein

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: focal adhesion; plasma membrane

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; protein complex binding

Biological Process: synaptic transmission; axon guidance; positive regulation of angiogenesis; metabolic process; leukocyte differentiation; Ras protein signal transduction; regulation of protein kinase B signaling cascade; negative regulation of cell migration

Research Articles on RRAS

Similar Products

Product Notes

The RRAS rras (Catalog #AAA834030) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's R Ras can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the RRAS rras for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "R Ras, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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