Testing Data
(Immunocytochemistry of HeLa cells using anti- Pyruvate Dehydrogenase (C-terminus) antibody diluted 1:150.)
Mouse anti-Human, Mouse Pyruvate Dehydrogenase Monoclonal Antibody | anti-PDHA antibody
Pyruvate Dehydrogenase Antibody
Testing Data
(Immunocytochemistry of HeLa cells using anti- Pyruvate Dehydrogenase (C-terminus) antibody diluted 1:150.)
Testing Data
(Immunocytochemistry of HeLa cells using anti- Pyruvate Dehydrogenase (C-terminus) antibody diluted 1:150.)
Testing Data #2
(Western blot detection of Pyruvate Dehydrogenase (C-terminus) antibody in 293,1299,mEsc&Tc1 cell lysates using Pyruvate Dehydrogenase(C-terminus) antibody (1:1000 diluted). Predicted band size: 43KDa Observed band size: 43KDa.)
Testing Data #2
(Western blot detection of Pyruvate Dehydrogenase (C-terminus) antibody in 293,1299,mEsc&Tc1 cell lysates using Pyruvate Dehydrogenase(C-terminus) antibody (1:1000 diluted). Predicted band size: 43KDa Observed band size: 43KDa.)
Entrez Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI Description
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
Uniprot Description
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, and thereby links the glycolytic pathway to the tricarboxylic cycle.
Research Articles on PDHA
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Product Notes
The PDHA pdha1 (Catalog #AAA857837) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Pyruvate Dehydrogenase Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Pyruvate Dehydrogenase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the PDHA pdha1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pyruvate Dehydrogenase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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