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Rat anti-Mouse PTX3 Monoclonal Antibody | anti-PTX3 antibody

PTX3 (Long Pentraxin, TSG14)

Gene Names
PTX3; TSG-14; TNFAIP5
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein G affinity chromatography.
Synonyms
PTX3; Monoclonal Antibody; PTX3 (Long Pentraxin; TSG14); Anti -PTX3 (Long Pentraxin; anti-PTX3 antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
7H62
Specificity
Recognizes mouse PTX3.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile ddH2O or sterile 40-50% glycerol.
Applicable Applications for anti-PTX3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot and ELISA.
Immunogen
NS0-derived recombinant mouse PTX3 (aa18-381) Accession # P48759
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-PTX3 antibody
Pentraxin 3 (PTX3), also known as TSG-14, belongs to the pentraxin family, which was named originally for the homopentameric structure formed by its members. PTX3/TSG-14 is a long pentraxin that contains a pentraxin-like domain at its carboxy-terminus with amino acid sequence similarity with short pentraxins (C-reactive protein and serum amyloid P component). PTX3 is a marker of the acute phase response and is highly expressed in advanced atherosclerotic plaques.
Product Categories/Family for anti-PTX3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,976 Da
NCBI Official Full Name
pentraxin-related protein PTX3
NCBI Official Synonym Full Names
pentraxin 3, long
NCBI Official Symbol
PTX3
NCBI Official Synonym Symbols
TSG-14; TNFAIP5
NCBI Protein Information
pentraxin-related protein PTX3; pentraxin-3; OTTHUMP00000213379; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor necrosis factor-inducible gene 14 protein; pentraxin-related gene, rapidly induced by IL-1 beta; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
UniProt Protein Name
Pentraxin-related protein PTX3
Protein Family
UniProt Gene Name
PTX3
UniProt Synonym Gene Names
TNFAIP5; TSG14
UniProt Entry Name
PTX3_HUMAN

Uniprot Description

PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3q25

Cellular Component: extracellular space; extracellular region

Molecular Function: complement component C1q binding; zymosan binding; virion binding

Biological Process: positive regulation of nitric oxide biosynthetic process; negative regulation of virion penetration into host cell; positive regulation of phagocytosis; innate immune response; response to yeast; opsonization; inflammatory response

Research Articles on PTX3

Similar Products

Product Notes

The PTX3 ptx3 (Catalog #AAA601109) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The PTX3 (Long Pentraxin, TSG14) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PTX3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot and ELISA. Researchers should empirically determine the suitability of the PTX3 ptx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTX3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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