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Western Blot (WB) (Western Blot detection against Immunogen (37.11kD).)

Mouse PSMA8 Monoclonal Antibody | anti-PSMA8 antibody

PSMA8 (Proteasome Subunit alpha Type-7-like, PSMA7L, MGC26605) (AP)

Gene Names
PSMA8; PSMA7L
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PSMA8; Monoclonal Antibody; PSMA8 (Proteasome Subunit alpha Type-7-like; PSMA7L; MGC26605) (AP); anti-PSMA8 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2E3
Specificity
Recognizes human PSMA8. Species Crossreactivity: mouse and rat.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-PSMA8 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Partial recombinant protein corresponding to aa143-243 from human PSMA8 (NP_653263) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
GFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGRNIELAIIRRNQPLKMFSAKEVELYVTEIEK
Conjugate
AP
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (37.11kD).)

Western Blot (WB) (Western Blot detection against Immunogen (37.11kD).)

Western Blot (WB)

(PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in PC-12.)

Western Blot (WB) (PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in PC-12.)

Western Blot (WB)

(PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in Jurkat.)

Western Blot (WB) (PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in Jurkat.)

Western Blot (WB)

(PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in NIH/3T3.)

Western Blot (WB) (PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in NIH/3T3.)

Western Blot (WB)

(PSMA8 monoclonal antibody, Western Blot analysis of PSMA8 expression in K-562.)

Western Blot (WB) (PSMA8 monoclonal antibody, Western Blot analysis of PSMA8 expression in K-562.)
Related Product Information for anti-PSMA8 antibody
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This may be a testis-specific subunit.
Product Categories/Family for anti-PSMA8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28kDa
NCBI Official Full Name
proteasome subunit alpha-type 8 isoform 1
NCBI Official Synonym Full Names
proteasome subunit alpha 8
NCBI Official Symbol
PSMA8
NCBI Official Synonym Symbols
PSMA7L
NCBI Protein Information
proteasome subunit alpha-type 8; proteasome subunit alpha type-7-like
UniProt Protein Name
Proteasome subunit alpha type-7-like
Protein Family
UniProt Gene Name
PSMA8
UniProt Synonym Gene Names
PSMA7L
UniProt Entry Name
PSA7L_HUMAN

Uniprot Description

PSMA8: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This may be a testis-specific subunit. Belongs to the peptidase T1A family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.25.1; Protease; Proteasome complex

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: nucleus; cytosol

Molecular Function: threonine endopeptidase activity

Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; negative regulation of apoptosis

Research Articles on PSMA8

Similar Products

Product Notes

The PSMA8 psma8 (Catalog #AAA6133183) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PSMA8 (Proteasome Subunit alpha Type-7-like, PSMA7L, MGC26605) (AP) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PSMA8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PSMA8 psma8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSMA8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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