Mouse anti-Human PSCA Monoclonal Antibody | anti-PSCA antibody
PSCA (Prostate Stem Cell Antigen, PRO232) (Biotin)
Gene Names
PSCA; PRO232
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified
Synonyms
PSCA; Monoclonal Antibody; PSCA (Prostate Stem Cell Antigen; PRO232) (Biotin); anti-PSCA antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
5C2
Specificity
Recognizes human PSCA.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-PSCA antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Recombinant protein corresponding to aa23-95 from human PSCA with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
CYSCKAQVSNEDCLQVENCTQLGEQCWTARIRAVGLLTVISKGCSLNCVDDSQDYYVGKKNITCCDTDLCNAS
Conjugate
Biotin
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-PSCA antibody
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene has a nonsynonymous nucleotide polymorphism at its start codon.
Product Categories/Family for anti-PSCA antibody
References
1. EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERS Klee, George G. ;Vasmatzis, George;Kosari, Farhad;Klee, Eric W. FreshPatents.com
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13kDa
NCBI Official Full Name
prostate stem cell antigen preproprotein
NCBI Official Synonym Full Names
prostate stem cell antigen
NCBI Official Symbol
PSCA
NCBI Official Synonym Symbols
PRO232
NCBI Protein Information
prostate stem cell antigen
UniProt Protein Name
Prostate stem cell antigen
Protein Family
UniProt Gene Name
PSCA
UniProt Entry Name
PSCA_HUMAN
NCBI Description
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Uniprot Description
PSCA: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 8q24.2
Cellular Component: plasma membrane
Research Articles on PSCA
Similar Products
Product Notes
The PSCA psca (Catalog #AAA6145533) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PSCA (Prostate Stem Cell Antigen, PRO232) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSCA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PSCA psca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSCA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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