Rabbit anti-Human PRSS3 Monoclonal Antibody | anti-PRSS3 antibody
Recombinant Anti-PRSS3 Antibody, Rabbit Monoclonal
Gene Names
PRSS3; T9; MTG; TRY3; TRY4; PRSS4
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
PRSS3; Monoclonal Antibody; Recombinant Anti-PRSS3 Antibody; Rabbit Monoclonal; Trypsin-3/PRSS3 Antibody; Rabbit MAb; protease; serine 3; Anti-MTG Antibody; Anti-PRSS4 Antibody; Anti-RP11-176F3.3 Antibody; Anti-T9 Antibody; Anti-TRY3 Antibody; Anti-TRY4 Antibody; anti-PRSS3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
001
Specificity
Human Trypsin-3/PRSS3
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-PRSS3 antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-1:10,000
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human Trypsin-3/PRSS3 protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human Trypsin-3/PRSS3 (rh Trypsin-3/PRSS3).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-PRSS3 antibody
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3/PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3/PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of CP. The trypsin inhibitor-degrading activity qualified PRSS3 as a candidate for a novel CP susceptibility gene. Trypsin-3/PRSS3 has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma.
Product Categories/Family for anti-PRSS3 antibody
References
Venter JC. et al., 2001, Science 291:1304-51. Marsit, CJ. et al., 2005, Mol Carcinog 44 (2):146-50. Rowen, L. et al., 2005, Mol Biol Evol. 22 (8):1712-20. Rosendahl, J. et al., 2010, Pancreatology. 10 (2-3):243-9
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,924 Da
NCBI Official Full Name
trypsin-3 isoform 3 preproprotein
NCBI Official Synonym Full Names
protease, serine 3
NCBI Official Symbol
PRSS3
NCBI Official Synonym Symbols
T9; MTG; TRY3; TRY4; PRSS4
NCBI Protein Information
trypsin-3
UniProt Protein Name
Trypsin-3
UniProt Gene Name
PRSS3
UniProt Synonym Gene Names
PRSS4; TRY3; TRY4
UniProt Entry Name
TRY3_HUMAN
Uniprot Description
Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5.
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Product Notes
The PRSS3 prss3 (Catalog #AAA8105939) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-PRSS3 Antibody, Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRSS3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-1:10,000. Researchers should empirically determine the suitability of the PRSS3 prss3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRSS3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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