Mouse anti-Human Pro-Brain-Derived Neurotrophic Factor Monoclonal Antibody
Pro-Brain-Derived Neurotrophic Factor (Pro-BDNF)
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Pro-Brain-Derived Neurotrophic Factor; Monoclonal Antibody; Pro-Brain-Derived Neurotrophic Factor (Pro-BDNF); Anti -Pro-Brain-Derived Neurotrophic Factor (Pro-BDNF); anti-Pro-Brain-Derived Neurotrophic Factor antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
11D34
Specificity
Recognizes human Pro-BDNF. Shows no cross-reactivity with recombinant, human BDNF (mature), recombinant, human beta-NGF, recombinant, human NT-3, recombinant, human Pro-NT-3, recombinant, human NT-4, or recombinant, human Pro-NT-4.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS with 5% trehalose. Reconstitute with sterile PBS.
Applicable Applications for anti-Pro-Brain-Derived Neurotrophic Factor antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA and Immunohistochemistry.
Dilution: Direct ELISA: 0.5-1ug/ml
Immunohistochemistry: 25ug/ml
Dilution: Direct ELISA: 0.5-1ug/ml
Immunohistochemistry: 25ug/ml
Immunogen
Recombinant corresponding to human Pro-BDNF expressed in CHO cells (P23560).
Hybridoma
Myeloma cells with B cells from Balb/c mice.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Pro-Brain-Derived Neurotrophic Factor antibody
BDNF is a member of the NGF family of neurotrophic factors that are required for the differentiation and survival of neuronal subpopulations in the central and peripheral nervous systems. BDNF functions through interactions with the TrkB receptor tyrosine kinase and the low affinity neurotrophin receptor (NTR). The N-terminal pro region of BDNF is removed by tPA and furin to release biologically active BDNF. The propeptides of human and mouse BDNF share 93% sequence identity.
Product Categories/Family for anti-Pro-Brain-Derived Neurotrophic Factor antibody
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Product Notes
The Pro-Brain-Derived Neurotrophic Factor (Catalog #AAA641227) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Pro-Brain-Derived Neurotrophic Factor (Pro-BDNF) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Pro-Brain-Derived Neurotrophic Factor can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry. Dilution: Direct ELISA: 0.5-1ug/ml Immunohistochemistry: 25ug/ml. Researchers should empirically determine the suitability of the Pro-Brain-Derived Neurotrophic Factor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pro-Brain-Derived Neurotrophic Factor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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