Mouse Porteolipid Protein of Myelin Monoclonal Antibody | anti-PLP antibody
Mouse Anti Porteolipid Protein of Myelin
Applications
ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry
Purity
Ion exchange column.
Synonyms
Porteolipid Protein of Myelin; Monoclonal Antibody; Mouse Anti Porteolipid Protein of Myelin; PLP antibody; Proteolipid Protein of Myelin; Mouse antibody; PLP; LIPOPHILIN; PMD; MMPL; SPG2; PLP/DM20; anti-PLP antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
NYRPLP
Purity/Purification
Ion exchange column.
Concentration
1mg/ml in PBS (after reconstitution). (varies by lot)
Sequence Length
41
Applicable Applications for anti-PLP antibody
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes
Direct ELISA, Western Blot, Immunoprecipitation, immunohistochemistry.
By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig.
By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig.
Reconstitution
Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen
synthetic pPLP 139-151.
Preparation and Storage
In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
Antibody is shipped lyophilized at ambient temperature.
Related Product Information for anti-PLP antibody
Introduction: Lipophilin is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. PLP functions in myelination. plays a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations associated with PLP gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Two transcript variants encoding distinct isoforms have been identified for PLP gene.PLP is the major myelin protein from the central nervous system and plays an important role in the formation or maintenance of the multilamellar structure of myelin.
Product Categories/Family for anti-PLP antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015]
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Product Notes
The PLP (Catalog #AAA140090) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Porteolipid Protein of Myelin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC). Direct ELISA, Western Blot, Immunoprecipitation, immunohistochemistry. By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig. Researchers should empirically determine the suitability of the PLP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Porteolipid Protein of Myelin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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