Mouse Polyadenylate-Binding Protein-Interacting Protein 2 Monoclonal Antibody | anti-PAIP2 antibody
Mouse Anti Human Polyadenylate-Binding Protein-Interacting Protein 2
Gene Names
PAIP2; PAIP-2; PAIP2A
Applications
ELISA, Western Blot
Purity
PAIP2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Synonyms
Polyadenylate-Binding Protein-Interacting Protein 2; Monoclonal Antibody; Mouse Anti Human Polyadenylate-Binding Protein-Interacting Protein 2; PAIP2 Antibody; Mouse Anti Human; Poly(A) Binding Protein Interacting Protein 2; PABP- interacting protein 2; HSPC218; PAIP-2; PAIP2A; Polyadenylate-binding protein-interacting protein 2; PAIP2; MGC72018; anti-PAIP2 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b heavy chain
Clone Number
PAT1C12AT
Purity/Purification
PAIP2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Form/Format
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence Length
127
Applicable Applications for anti-PAIP2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
PAIP2 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000. Recommended starting dilution is 1:1000.
Immunogen
Anti-human PAIP2 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CMBL 1-127 amino acids purified from E Coli.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-PAIP2 antibody
Introduction: PAIP2 has a role as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. PAIP2 inhibitory activity on translation is mediated through its action on PABPC1. PAIP2 displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. PAIP2 association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Product Categories/Family for anti-PAIP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,984 Da
NCBI Official Full Name
polyadenylate-binding protein-interacting protein 2
NCBI Official Synonym Full Names
poly(A) binding protein interacting protein 2
NCBI Official Symbol
PAIP2
NCBI Official Synonym Symbols
PAIP-2; PAIP2A
NCBI Protein Information
polyadenylate-binding protein-interacting protein 2; PABC1-interacting protein 2; PABP-interacting protein 2; polyA-binding protein-interacting protein 2
UniProt Protein Name
Polyadenylate-binding protein-interacting protein 2
Protein Family
UniProt Gene Name
PAIP2
UniProt Synonym Gene Names
PAIP2A; PABP-interacting protein 2; PAIP-2; Poly(A)-binding protein-interacting protein 2
UniProt Entry Name
PAIP2_HUMAN
Uniprot Description
PAIP2: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. Interacts with the second and third RRM domains and C- terminus regions of PABPC1 in a 2:1 stoichiometry. Belongs to the PAIP2 family.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 5q31.2
Cellular Component: cytoplasm
Molecular Function: mRNA binding; protein binding; translation repressor activity
Biological Process: negative regulation of translational initiation; spermatogenesis; memory
Research Articles on PAIP2
1. Paip2 is a host antiviral restriction factor antagonized by PABP accumulation in HCMV-infected cells
Similar Products
Product Notes
The PAIP2 paip2 (Catalog #AAA140450) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Polyadenylate-Binding Protein-Interacting Protein 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). PAIP2 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000. Recommended starting dilution is 1:1000. Researchers should empirically determine the suitability of the PAIP2 paip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Polyadenylate-Binding Protein-Interacting Protein 2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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