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Quality Control (Western blot analysis of immunized recombinant protein, using anti-POLS monoclonal antibody. )

Mouse anti-Human POLS Monoclonal Antibody | anti-POLS antibody

Mouse monoclonal antibody Anti-Human POLS

Gene Names
PAPD7; LAK1; POLK; POLS; TRF4; LAK-1; TRF41; TRF4-1; TUTASE5
Reactivity
Human
Applications
Dot Blot
Synonyms
POLS; Monoclonal Antibody; Mouse monoclonal antibody Anti-Human POLS; Homo sapiens polymerase (DNA directed) sigma (POLS); mRNA.; POLK; TRF4; LAK-1; TRF4-1; anti-POLS antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2794C4a
Concentration
100 ug/ml (1.0 ml) (varies by lot)
Sequence Length
3871
Applicable Applications for anti-POLS antibody
Dot Blot (DB)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.

Quality Control

(Western blot analysis of immunized recombinant protein, using anti-POLS monoclonal antibody. )

Quality Control (Western blot analysis of immunized recombinant protein, using anti-POLS monoclonal antibody. )

Quality Control #2

(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)

Quality Control #2 (Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Related Product Information for anti-POLS antibody
The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. [NCBI Entrez Gene Summary]

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,874 Da
NCBI Official Full Name
Homo sapiens PAP associated domain containing 7 (PAPD7), transcript variant 1, mRNA
NCBI Official Synonym Full Names
PAP associated domain containing 7
NCBI Official Symbol
PAPD7
NCBI Official Synonym Symbols
LAK1; POLK; POLS; TRF4; LAK-1; TRF41; TRF4-1; TUTASE5
NCBI Protein Information
non-canonical poly(A) RNA polymerase PAPD7; non-canonical poly(A) RNA polymerase PAPD7; DNA polymerase kappa; DNA polymerase sigma; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; TUTase 5; polymerase (DNA directed) sigma; polymerase (DNA-directed) sigma; terminal uridylyltransferase 5; topoisomerase-related function protein 4-1
UniProt Protein Name
Non-canonical poly(A) RNA polymerase PAPD7
UniProt Gene Name
PAPD7
UniProt Entry Name
PAPD7_HUMAN

NCBI Description

The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]

Uniprot Description

POLS: DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Does not play a role in replication-dependent histone mRNA degradation. Belongs to the DNA polymerase type-B-like family.

Protein type: EC 2.7.7.19; DNA replication; Transferase; DNA repair, damage

Chromosomal Location of Human Ortholog: 5p15

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: polynucleotide adenylyltransferase activity; DNA binding; SMC protein binding; metal ion binding; DNA-directed DNA polymerase activity

Biological Process: response to drug; mitotic chromosome condensation; cell division; double-strand break repair; sister chromatid cohesion

Research Articles on POLS

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Product Notes

The POLS papd7 (Catalog #AAA120381) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human POLS reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's POLS can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB). Researchers should empirically determine the suitability of the POLS papd7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLS, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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