Rabbit anti-Human PLXDC1 Monoclonal Antibody | anti-PLXDC1 antibody
Rabbit anti Human PLXDC1 Monoclonal Antibody
Gene Names
PLXDC1; TEM3; TEM7
Reactivity
Human
Applications
ELISA
Synonyms
PLXDC1 ; Monoclonal Antibody; Rabbit anti Human PLXDC1 Monoclonal Antibody; anti-PLXDC1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Sequence Length
500
Applicable Applications for anti-PLXDC1 antibody
ELISA (EIA)
Application Notes
ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human PLXDC1. The detection limit for Human PLXDC1 is approximately 0.039 ng/well.
Immunogen
Recombinant Human TEM7/PLXDC1 protein
Buffer
0.2 mum filtered solution in PBS with 5% trehalose
Preparation and Storage
This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-PLXDC1 antibody
Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein which belongs to the plexin family. PLXDC1/TEM3 is detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1/TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1/TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1/TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1/TEM3 may be a molecular target for new strategies for proliferative diabetic retinopathy (PDR). PLXDC1/TEM3 interacts with NID1. It may also interact with CTTN.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,895 Da
NCBI Official Full Name
plexin domain-containing protein 1
NCBI Official Synonym Full Names
plexin domain containing 1
NCBI Official Symbol
PLXDC1
NCBI Official Synonym Symbols
TEM3; TEM7
NCBI Protein Information
plexin domain-containing protein 1
UniProt Protein Name
Plexin domain-containing protein 1
UniProt Gene Name
PLXDC1
UniProt Synonym Gene Names
TEM3; TEM7
UniProt Entry Name
PLDX1_HUMAN
Uniprot Description
PLXDC1: Plays a critical role in endothelial cell capillary morphogenesis. Belongs to the plexin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: receptor complex
Molecular Function: protein binding
Research Articles on PLXDC1
Similar Products
Product Notes
The PLXDC1 plxdc1 (Catalog #AAA2544282) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human PLXDC1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLXDC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human PLXDC1. The detection limit for Human PLXDC1 is approximately 0.039 ng/well. Researchers should empirically determine the suitability of the PLXDC1 plxdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLXDC1 , Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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