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Mouse Plakophilin 3 Monoclonal Antibody | anti-PKP3 antibody

Plakophilin 3 antibody

Reactivity
Bovine, Frog, Human, Mouse
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Culture supernatant
Synonyms
Plakophilin 3; Monoclonal Antibody; Plakophilin 3 antibody; Monoclonal Plakophilin 3; Anti-Plakophilin 3; anti-PKP3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Bovine, Frog, Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
PKP3-270.6.2
Specificity
Human plakophilin 3
Purity/Purification
Culture supernatant
Form/Format
Hybridoma culture supernatant.
Sequence Length
797
Applicable Applications for anti-PKP3 antibody
Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
Biological Significance
Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton.
Cross-Reactivity
Bovine, frog, human, mouse
Immunogen
Plakophilin 3 antibody was raised in mouse using recombinant protein (E Coli) of human plakophilin 3 as the immunogen.
Preparation and Storage
Store at 4 degree C.
Related Product Information for anti-PKP3 antibody
Mouse monoclonal Plakophilin 3 antibody
Product Categories/Family for anti-PKP3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
88,655 Da
NCBI Official Full Name
plakophilin-3 isoform PKP3a
NCBI Official Synonym Full Names
plakophilin 3
NCBI Official Symbol
PKP3
NCBI Protein Information
plakophilin-3
UniProt Protein Name
Plakophilin-3
Protein Family
UniProt Gene Name
PKP3
UniProt Entry Name
PKP3_HUMAN

NCBI Description

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Uniprot Description

plakophilin 3: a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells and dendritic reticular cells of lymphatic follicles.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: desmosome; plasma membrane; intercellular junction; nucleus

Molecular Function: cell adhesion molecule binding

Biological Process: cell-cell adhesion

Research Articles on PKP3

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Product Notes

The PKP3 pkp3 (Catalog #AAA531363) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Plakophilin 3 antibody reacts with Bovine, Frog, Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Plakophilin 3 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Western Blot (WB). Researchers should empirically determine the suitability of the PKP3 pkp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Plakophilin 3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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